A facile in situ generation of dithiocarbamate ligands for stable gold nanoparticle-oligonucleotide conjugates

Jaswinder Sharma, Rahul Chhabra, Hao Yan, Yan Liu

Research output: Contribution to journalArticlepeer-review

61 Citations (Scopus)

Abstract

Here we demonstrate a facile strategy of preparing gold nanoparticle (AuNP) and DNA conjugates by in situ generation of strong metal affinity capping ligands, dithiocarbamates (DTC) modified oligonucleotides; the conjugates produced are stable at elevated temperature, resistant to ligand displacement and preserve the functionality of the conjugated oligonucleotides.

Original languageEnglish
Pages (from-to)2140-2142
Number of pages3
JournalChemical Communications
Issue number18
DOIs
Publication statusPublished - 2008

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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