A Synthetic Strategy of Quantum Dot-Bioconjugate

Qiangbin Wang, Hao Yan, Dong Kyun Seo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Quantum dots (QDs) have attracted tremendous interest in biological applications, such as bioimaging, biolabeling, and biosensing, because of their advantages over organic fluorophores at high quantum yield (QY), size-tunable narrow emission, photostability, etc. To date, various strategies have been developed to obtain water-soluble QDs and QD bioconjugates, but these commonly require multiple steps to obtain the final products. Herein, we present a simple and robust one-step method for creating stable, water-soluble QD and QD-biomolecule conjugates. We demonstrate the successful implementation of this strategy by using mercaptopropyl acid and DNA molecules as model systems, but expect this could also be extended to other types of biomolecules.

Original languageEnglish
Title of host publicationINEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings
Pages332-333
Number of pages2
DOIs
Publication statusPublished - May 5 2010
Event2010 3rd International Nanoelectronics Conference, INEC 2010 - Hongkong, China
Duration: Jan 3 2010Jan 8 2010

Publication series

NameINEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings

Other

Other2010 3rd International Nanoelectronics Conference, INEC 2010
CountryChina
CityHongkong
Period1/3/101/8/10

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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    Wang, Q., Yan, H., & Seo, D. K. (2010). A Synthetic Strategy of Quantum Dot-Bioconjugate. In INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings (pp. 332-333). [5424726] (INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings). https://doi.org/10.1109/INEC.2010.5424726