Artificial enzymes formed through directed assembly of molecular square encapsulated epoxidation catalysts

Melissa L. Merlau, Maria Del Pilar Mejia, Sonbinh T. Nguyen, Joseph T Hupp

Research output: Contribution to journalArticle

333 Citations (Scopus)

Abstract

Supramolecular complex formation imparts stability and substrate selectivity to a simple manganese-porphyrin-based epoxidation catalyst. Lewis acid/Lewis base directed assembly was used to encapsulate the epoxidation catalyst within a supramolecular square structure to form an enzyme-like catalyst system. The "molecular square" (see picture) takes on the functions of the protein superstructure in an enzyme: it spatially protects the catalytic core from decomposition and induces reaction selectivity.

Original languageEnglish
Pages (from-to)4239-4242
Number of pages4
JournalAngewandte Chemie - International Edition
Volume40
Issue number22
DOIs
Publication statusPublished - Nov 19 2001

Fingerprint

Epoxidation
Enzymes
Catalysts
Lewis Bases
Lewis Acids
Catalyst selectivity
Porphyrins
Manganese
Decomposition
Proteins
Acids
Substrates

Keywords

  • Epoxidation
  • Homogenous catalysis
  • Host-guest systems
  • Self-assembly
  • Supramolecular chemistry

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Artificial enzymes formed through directed assembly of molecular square encapsulated epoxidation catalysts. / Merlau, Melissa L.; Mejia, Maria Del Pilar; Nguyen, Sonbinh T.; Hupp, Joseph T.

In: Angewandte Chemie - International Edition, Vol. 40, No. 22, 19.11.2001, p. 4239-4242.

Research output: Contribution to journalArticle

Merlau, Melissa L. ; Mejia, Maria Del Pilar ; Nguyen, Sonbinh T. ; Hupp, Joseph T. / Artificial enzymes formed through directed assembly of molecular square encapsulated epoxidation catalysts. In: Angewandte Chemie - International Edition. 2001 ; Vol. 40, No. 22. pp. 4239-4242.
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