Abstract
Covalently linked carotenoid-porphyrin (C-P) dyads that mimic the photochemistry of carotenoids in photosynthetic membranes have been synthesized. Singlet energy transfer (C to P), triplet energy transfer (P to C), and quenching of P* by electron transfer from C to P*, have been observed and the structural requirements for these processes defined. A monolayer system has been developed in which a carotenoid bearing a terminal amino group is photoelectrochemically active. This demonstrates that carotenoid pigments could act as blue light photoreceptor pigments. A carotenoporphyrin for use as an imaging agent for tumor tissue detection has been synthesized and tested in vivo. This compound incorportates carotenoid photoprotection against singlet oxygen and is therefore not phototoxic.
| Original language | English |
|---|---|
| Pages (from-to) | 1033-1040 |
| Number of pages | 8 |
| Journal | Pure and Applied Chemistry |
| Volume | 66 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Jan 1 1994 |
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ASJC Scopus subject areas
- Chemical Engineering(all)
- Chemistry(all)
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Carotenoids : Nature's unique pigments for light and energy processing. / Moore, Thomas A; Gust, John Devens; Moore, Ana L.
In: Pure and Applied Chemistry, Vol. 66, No. 5, 01.01.1994, p. 1033-1040.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Carotenoids
T2 - Nature's unique pigments for light and energy processing
AU - Moore, Thomas A
AU - Gust, John Devens
AU - Moore, Ana L
PY - 1994/1/1
Y1 - 1994/1/1
N2 - Covalently linked carotenoid-porphyrin (C-P) dyads that mimic the photochemistry of carotenoids in photosynthetic membranes have been synthesized. Singlet energy transfer (C to P), triplet energy transfer (P to C), and quenching of P* by electron transfer from C to P*, have been observed and the structural requirements for these processes defined. A monolayer system has been developed in which a carotenoid bearing a terminal amino group is photoelectrochemically active. This demonstrates that carotenoid pigments could act as blue light photoreceptor pigments. A carotenoporphyrin for use as an imaging agent for tumor tissue detection has been synthesized and tested in vivo. This compound incorportates carotenoid photoprotection against singlet oxygen and is therefore not phototoxic.
AB - Covalently linked carotenoid-porphyrin (C-P) dyads that mimic the photochemistry of carotenoids in photosynthetic membranes have been synthesized. Singlet energy transfer (C to P), triplet energy transfer (P to C), and quenching of P* by electron transfer from C to P*, have been observed and the structural requirements for these processes defined. A monolayer system has been developed in which a carotenoid bearing a terminal amino group is photoelectrochemically active. This demonstrates that carotenoid pigments could act as blue light photoreceptor pigments. A carotenoporphyrin for use as an imaging agent for tumor tissue detection has been synthesized and tested in vivo. This compound incorportates carotenoid photoprotection against singlet oxygen and is therefore not phototoxic.
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U2 - 10.1351/pac199466051033
DO - 10.1351/pac199466051033
M3 - Article
VL - 66
SP - 1033
EP - 1040
JO - Pure and Applied Chemistry
JF - Pure and Applied Chemistry
SN - 0033-4545
IS - 5
ER -