Abstract
Catalytic ionic hydrogenation of ketones occurs by proton transfer to a ketone from a cationic metal dihydride, followed by hydride transfer from a neutral metal hydride. This contrasts with traditional catalysts for ketone hydrogenation that require binding of the ketone to the metal and subsequent insertion of the ketone into a M-H bond. Ionic hydrogenation catalysts based on the inexpensive metals molybdenum and tungsten have been developed based on mechanistic understanding of the individual steps required in the catalytic reaction.
Original language | English |
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Pages (from-to) | 2366-2374 |
Number of pages | 9 |
Journal | Chemistry - A European Journal |
Volume | 10 |
Issue number | 10 |
DOIs | |
Publication status | Published - May 17 2004 |
Keywords
- Homogeneous catalysis
- Hydride ligands
- Hydride transfer
- Hydrogenation
- Protonation
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry