Catalytic, oxidant-free, direct olefination of alcohols using Wittig reagents

E. Khaskin, David Milstein

Research output: Contribution to journal › Article

15 Citations (Scopus)

Abstract

Reported here is the catalytic, acceptorless coupling of alcohols with in situ generated, non-stabilized phosphonium ylides to form olefins as major products. The reaction uses low catalyst loadings and does not require added oxidants. Hydrogenation of the product is minimized and the reaction leads to Z (aliphatic) or E (benzylic) stereospecificity.

Original languageEnglish
Pages (from-to)9002-9005
Number of pages4
JournalChemical Communications
Volume51
Issue number43
DOIs
Publication statusPublished - May 28 2015

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Alkenes
Oxidants
Olefins
Hydrogenation
Alcohols
Catalysts

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys

Cite this

Catalytic, oxidant-free, direct olefination of alcohols using Wittig reagents. / Khaskin, E.; Milstein, David.

In: Chemical Communications, Vol. 51, No. 43, 28.05.2015, p. 9002-9005.

Research output: Contribution to journal › Article

Khaskin, E & Milstein, D 2015, 'Catalytic, oxidant-free, direct olefination of alcohols using Wittig reagents', Chemical Communications, vol. 51, no. 43, pp. 9002-9005. https://doi.org/10.1039/c5cc02902c
Khaskin E, Milstein D. Catalytic, oxidant-free, direct olefination of alcohols using Wittig reagents. Chemical Communications. 2015 May 28;51(43):9002-9005. https://doi.org/10.1039/c5cc02902c
Khaskin, E. ; Milstein, David. / Catalytic, oxidant-free, direct olefination of alcohols using Wittig reagents. In: Chemical Communications. 2015 ; Vol. 51, No. 43. pp. 9002-9005.
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