Cationic, neutral, and anionic PNP PdII and PtII complexes

Dearomatization by deprotonation and double-deprotonation of pincer systems

Moran Feller, Eyal Ben-Ari, Mark A. Iron, Yael Diskin-Posner, Gregory Leitus, Linda J. Linda, Leonid Konstantinovski, David Milstein

Research output: Contribution to journalArticle

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Abstract

A series of cationic, neutral, and anionic PdII and Pt II PNP (PNP = 2, 6-bis-(di-tert-butylphosphinomethyl)pyridine) complexes were synthesized. The neutral, dearomatized complexes [(PNP*)MX] (PNP* = deprotonated PNP; M= Pd, Pt; X = Cl, Me) were prepared by deprotonation of the PNP methylene group of the corresponding cationic complexes [(PNP)MX][Cl] with 1 equiv of base (KN(SiMe3)2 or tBuOK), while the anionic complexes [(PNP*)MX] -Y+ (PNP* = double-deprotonated PNP; Y = Li, K) were prepared by deprotonation of the two methylene groups of the corresponding cationic complexes with either 2 equiv of KN(SiMe3)2 or an excess of MeLi. While the reaction of [(PNP)PtCl][Cl] with an excess of MeLi led only to the anionic complex without chloride substitution, reaction of [(PNP)PdCl][Cl] with an excess of MeLi led to the methylated anionic complex [(PNP*)PdMe]-Li+. NMR studies, X-ray structures, and density functional theory (DFT) calculations reveal that the neutral complexes have a broken aromatic system with alternating single and double bonds, and the deprotonated arm is bound to the ring by an exocyclic CdC double bond. The anionic complexes are best described as a π system comprising the ring carbons conjugated with the exocyclic double bonds of the deprotonated "arms". The neutral complexes are reversibly protonated to their cationic analogues by water or methanol. The thermodynamic parameters.δ H, δ S, and δ G for the reversible protonation of the neutral complexes by methanol were obtained.

Original languageEnglish
Pages (from-to)1615-1625
Number of pages11
JournalInorganic Chemistry
Volume49
Issue number4
DOIs
Publication statusPublished - Feb 15 2010

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Deprotonation
methylene
Methanol
methyl alcohol
rings
Protonation
Density functional theory
Chlorides
pyridines
Substitution reactions
Carbon
chlorides
Nuclear magnetic resonance
Thermodynamics
substitutes
analogs
density functional theory
X rays
thermodynamics
nuclear magnetic resonance

ASJC Scopus subject areas

  • Inorganic Chemistry
  • Physical and Theoretical Chemistry

Cite this

Cationic, neutral, and anionic PNP PdII and PtII complexes : Dearomatization by deprotonation and double-deprotonation of pincer systems. / Feller, Moran; Ben-Ari, Eyal; Iron, Mark A.; Diskin-Posner, Yael; Leitus, Gregory; Linda, Linda J.; Konstantinovski, Leonid; Milstein, David.

In: Inorganic Chemistry, Vol. 49, No. 4, 15.02.2010, p. 1615-1625.

Research output: Contribution to journalArticle

Feller, M, Ben-Ari, E, Iron, MA, Diskin-Posner, Y, Leitus, G, Linda, LJ, Konstantinovski, L & Milstein, D 2010, 'Cationic, neutral, and anionic PNP PdII and PtII complexes: Dearomatization by deprotonation and double-deprotonation of pincer systems', Inorganic Chemistry, vol. 49, no. 4, pp. 1615-1625. https://doi.org/10.1021/ic902012z
Feller, Moran ; Ben-Ari, Eyal ; Iron, Mark A. ; Diskin-Posner, Yael ; Leitus, Gregory ; Linda, Linda J. ; Konstantinovski, Leonid ; Milstein, David. / Cationic, neutral, and anionic PNP PdII and PtII complexes : Dearomatization by deprotonation and double-deprotonation of pincer systems. In: Inorganic Chemistry. 2010 ; Vol. 49, No. 4. pp. 1615-1625.
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abstract = "A series of cationic, neutral, and anionic PdII and Pt II PNP (PNP = 2, 6-bis-(di-tert-butylphosphinomethyl)pyridine) complexes were synthesized. The neutral, dearomatized complexes [(PNP*)MX] (PNP* = deprotonated PNP; M= Pd, Pt; X = Cl, Me) were prepared by deprotonation of the PNP methylene group of the corresponding cationic complexes [(PNP)MX][Cl] with 1 equiv of base (KN(SiMe3)2 or tBuOK), while the anionic complexes [(PNP*)MX] -Y+ (PNP* = double-deprotonated PNP; Y = Li, K) were prepared by deprotonation of the two methylene groups of the corresponding cationic complexes with either 2 equiv of KN(SiMe3)2 or an excess of MeLi. While the reaction of [(PNP)PtCl][Cl] with an excess of MeLi led only to the anionic complex without chloride substitution, reaction of [(PNP)PdCl][Cl] with an excess of MeLi led to the methylated anionic complex [(PNP*)PdMe]-Li+. NMR studies, X-ray structures, and density functional theory (DFT) calculations reveal that the neutral complexes have a broken aromatic system with alternating single and double bonds, and the deprotonated arm is bound to the ring by an exocyclic CdC double bond. The anionic complexes are best described as a π system comprising the ring carbons conjugated with the exocyclic double bonds of the deprotonated {"}arms{"}. The neutral complexes are reversibly protonated to their cationic analogues by water or methanol. The thermodynamic parameters.δ H, δ S, and δ G for the reversible protonation of the neutral complexes by methanol were obtained.",
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AU - Feller, Moran

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AU - Iron, Mark A.

AU - Diskin-Posner, Yael

AU - Leitus, Gregory

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AU - Konstantinovski, Leonid

AU - Milstein, David

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N2 - A series of cationic, neutral, and anionic PdII and Pt II PNP (PNP = 2, 6-bis-(di-tert-butylphosphinomethyl)pyridine) complexes were synthesized. The neutral, dearomatized complexes [(PNP*)MX] (PNP* = deprotonated PNP; M= Pd, Pt; X = Cl, Me) were prepared by deprotonation of the PNP methylene group of the corresponding cationic complexes [(PNP)MX][Cl] with 1 equiv of base (KN(SiMe3)2 or tBuOK), while the anionic complexes [(PNP*)MX] -Y+ (PNP* = double-deprotonated PNP; Y = Li, K) were prepared by deprotonation of the two methylene groups of the corresponding cationic complexes with either 2 equiv of KN(SiMe3)2 or an excess of MeLi. While the reaction of [(PNP)PtCl][Cl] with an excess of MeLi led only to the anionic complex without chloride substitution, reaction of [(PNP)PdCl][Cl] with an excess of MeLi led to the methylated anionic complex [(PNP*)PdMe]-Li+. NMR studies, X-ray structures, and density functional theory (DFT) calculations reveal that the neutral complexes have a broken aromatic system with alternating single and double bonds, and the deprotonated arm is bound to the ring by an exocyclic CdC double bond. The anionic complexes are best described as a π system comprising the ring carbons conjugated with the exocyclic double bonds of the deprotonated "arms". The neutral complexes are reversibly protonated to their cationic analogues by water or methanol. The thermodynamic parameters.δ H, δ S, and δ G for the reversible protonation of the neutral complexes by methanol were obtained.

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