Characterizing the Quantum-Confined Stark Effect in Semiconductor Quantum Dots and Nanorods for Single-Molecule Electrophysiology

Yung Kuo; Jack Li; Xavier Michalet; Alexey Chizhik; Noga Meir; Omri Bar-Elli; Emory Chan; Dan Oron; Joerg Enderlein; Shimon Weiss

doi:10.1021/acsphotonics.8b00617

Characterizing the Quantum-Confined Stark Effect in Semiconductor Quantum Dots and Nanorods for Single-Molecule Electrophysiology

Yung Kuo, Jack Li, Xavier Michalet, Alexey Chizhik, Noga Meir, Omri Bar-Elli, Emory Chan, Dan Oron, Joerg Enderlein, Shimon Weiss

Weizmann Institute of Science, Israel

Research output: Contribution to journal › Article

8 Citations (Scopus)

Abstract

We optimized the performance of quantum-confined Stark effect (QCSE)-based voltage nanosensors. A high-throughput approach for single-particle QCSE characterization was developed and utilized to screen a library of such nanosensors. Type-II ZnSe/CdS-seeded nanorods were found to have the best performance among the different nanosensors evaluated in this work. The degree of correlation between intensity changes and spectral changes of the exciton's emission under an applied field was characterized. An upper limit for the temporal response of individual ZnSe/CdS nanorods to voltage modulation was characterized by high-throughput, high temporal resolution intensity measurements using a novel photon-counting camera. The measured 3.5 μs response time is limited by the voltage modulation electronics and represents ∼30 times higher bandwidth than needed for recording an action potential in a neuron.

Original language	English
Pages (from-to)	4788-4800
Number of pages	13
Journal	ACS Photonics
Volume	5
Issue number	12
DOIs	https://doi.org/10.1021/acsphotonics.8b00617
Publication status	Published - Dec 19 2018

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Keywords

membrane potential
nanorod
quantum dot
quantum-confined Stark effect
single molecule
voltage sensor

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biotechnology
Atomic and Molecular Physics, and Optics
Electrical and Electronic Engineering

Cite this

Kuo, Y., Li, J., Michalet, X., Chizhik, A., Meir, N., Bar-Elli, O., Chan, E., Oron, D., Enderlein, J., & Weiss, S. (2018). Characterizing the Quantum-Confined Stark Effect in Semiconductor Quantum Dots and Nanorods for Single-Molecule Electrophysiology. ACS Photonics, 5(12), 4788-4800. https://doi.org/10.1021/acsphotonics.8b00617

Characterizing the Quantum-Confined Stark Effect in Semiconductor Quantum Dots and Nanorods for Single-Molecule Electrophysiology. / Kuo, Yung; Li, Jack; Michalet, Xavier; Chizhik, Alexey; Meir, Noga; Bar-Elli, Omri; Chan, Emory; Oron, Dan; Enderlein, Joerg; Weiss, Shimon.

In: ACS Photonics, Vol. 5, No. 12, 19.12.2018, p. 4788-4800.

Research output: Contribution to journal › Article

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Access to Document

10.1021/acsphotonics.8b00617