Characterizing the Quantum-Confined Stark Effect in Semiconductor Quantum Dots and Nanorods for Single-Molecule Electrophysiology

Yung Kuo, Jack Li, Xavier Michalet, Alexey Chizhik, Noga Meir, Omri Bar-Elli, Emory Chan, Dan Oron, Joerg Enderlein, Shimon Weiss

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We optimized the performance of quantum-confined Stark effect (QCSE)-based voltage nanosensors. A high-throughput approach for single-particle QCSE characterization was developed and utilized to screen a library of such nanosensors. Type-II ZnSe/CdS-seeded nanorods were found to have the best performance among the different nanosensors evaluated in this work. The degree of correlation between intensity changes and spectral changes of the exciton's emission under an applied field was characterized. An upper limit for the temporal response of individual ZnSe/CdS nanorods to voltage modulation was characterized by high-throughput, high temporal resolution intensity measurements using a novel photon-counting camera. The measured 3.5 μs response time is limited by the voltage modulation electronics and represents ∼30 times higher bandwidth than needed for recording an action potential in a neuron.

Original languageEnglish
JournalACS Photonics
DOIs
Publication statusAccepted/In press - Jan 1 2018

Fingerprint

electrophysiology
Nanosensors
Electrophysiology
Stark effect
Nanotubes
Quantum Dots
Semiconductors
Nanorods
nanorods
Semiconductor quantum dots
quantum dots
Molecules
Electric potential
electric potential
Photons
Throughput
Modulation
Action Potentials
Libraries
Reaction Time

Keywords

  • membrane potential
  • nanorod
  • quantum dot
  • quantum-confined Stark effect
  • single molecule
  • voltage sensor

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biotechnology
  • Atomic and Molecular Physics, and Optics
  • Electrical and Electronic Engineering

Cite this

Characterizing the Quantum-Confined Stark Effect in Semiconductor Quantum Dots and Nanorods for Single-Molecule Electrophysiology. / Kuo, Yung; Li, Jack; Michalet, Xavier; Chizhik, Alexey; Meir, Noga; Bar-Elli, Omri; Chan, Emory; Oron, Dan; Enderlein, Joerg; Weiss, Shimon.

In: ACS Photonics, 01.01.2018.

Research output: Contribution to journalArticle

Kuo, Yung ; Li, Jack ; Michalet, Xavier ; Chizhik, Alexey ; Meir, Noga ; Bar-Elli, Omri ; Chan, Emory ; Oron, Dan ; Enderlein, Joerg ; Weiss, Shimon. / Characterizing the Quantum-Confined Stark Effect in Semiconductor Quantum Dots and Nanorods for Single-Molecule Electrophysiology. In: ACS Photonics. 2018.
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