Chirality on surfaces Modeling and behaviour

Irina Paci, Igal Szleifer, Mark A. Ratner

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Chirality has been a fascinating topic in chemistry, ever since its first observation by Biot in 1815. Its molecular basis was first understood by Pasteur in 1848. Enantiomers, identical in every way but mirror-images of each other, have similar physical properties, behave identically in chemical reactions with achiral molecules, but have very different interactions with chiral molecules. In recent decades, chirality has become an important direction in pharmaceutical research, as many drugs have stereoselective activity. This review focuses on a new aspect of chiral resolution on solid surfaces, and relationships between molecular structure, thermodynamic effects, and the result of chiral surface self-organization.

Original languageEnglish
Pages (from-to)18-22
Number of pages5
JournalChimica Oggi
Volume25
Issue number5 SUPPL. 2
Publication statusPublished - Nov 19 2007

ASJC Scopus subject areas

  • Chemistry(all)

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    Paci, I., Szleifer, I., & Ratner, M. A. (2007). Chirality on surfaces Modeling and behaviour. Chimica Oggi, 25(5 SUPPL. 2), 18-22.