Chirality on surfaces Modeling and behaviour

Irina Paci, Igal Szleifer, Mark A Ratner

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Chirality has been a fascinating topic in chemistry, ever since its first observation by Biot in 1815. Its molecular basis was first understood by Pasteur in 1848. Enantiomers, identical in every way but mirror-images of each other, have similar physical properties, behave identically in chemical reactions with achiral molecules, but have very different interactions with chiral molecules. In recent decades, chirality has become an important direction in pharmaceutical research, as many drugs have stereoselective activity. This review focuses on a new aspect of chiral resolution on solid surfaces, and relationships between molecular structure, thermodynamic effects, and the result of chiral surface self-organization.

Original languageEnglish
Pages (from-to)18-22
Number of pages5
JournalChimica Oggi
Volume25
Issue number5 SUPPL. 2
Publication statusPublished - 2007

Fingerprint

Chirality
Molecular Structure
Thermodynamics
Observation
Molecules
Enantiomers
Pharmaceutical Preparations
Molecular structure
Chemical reactions
Mirrors
Physical properties
Direction compound
Pharmaceutical Research

ASJC Scopus subject areas

  • Chemistry(all)
  • Biotechnology

Cite this

Paci, I., Szleifer, I., & Ratner, M. A. (2007). Chirality on surfaces Modeling and behaviour. Chimica Oggi, 25(5 SUPPL. 2), 18-22.

Chirality on surfaces Modeling and behaviour. / Paci, Irina; Szleifer, Igal; Ratner, Mark A.

In: Chimica Oggi, Vol. 25, No. 5 SUPPL. 2, 2007, p. 18-22.

Research output: Contribution to journalArticle

Paci, I, Szleifer, I & Ratner, MA 2007, 'Chirality on surfaces Modeling and behaviour', Chimica Oggi, vol. 25, no. 5 SUPPL. 2, pp. 18-22.
Paci I, Szleifer I, Ratner MA. Chirality on surfaces Modeling and behaviour. Chimica Oggi. 2007;25(5 SUPPL. 2):18-22.
Paci, Irina ; Szleifer, Igal ; Ratner, Mark A. / Chirality on surfaces Modeling and behaviour. In: Chimica Oggi. 2007 ; Vol. 25, No. 5 SUPPL. 2. pp. 18-22.
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