Chlorination of (Phebox)Ir(mesityl)(OAc) by thionyl chloride

Meng Zhou, Alan S Goldman

Research output: Contribution to journalArticle

Abstract

Pincer (Phebox)Ir(mesityl)(OAc) (2) (Phebox = 3,5-dimethylphenyl-2,6-bis(oxazolinyl)) complex, formed by benzylic C-H activation of mesitylene (1,3,5-trimethylbenzene) using (Phebox)Ir(OAc)2OH2 (1), was treated with thionyl chloride to rapidly form 1-(chloromethyl)-3,5-dimethylbenzene in 50% yield at 23 ° C. A green species was obtained at the end of reaction, which decomposed during flash column chromatography to form (Phebox)IrCl2OH2 in 87% yield.

Original languageEnglish
Pages (from-to)10122-10130
Number of pages9
JournalMolecules
Volume20
Issue number6
DOIs
Publication statusPublished - Jun 1 2015

Fingerprint

chlorination
Chlorination
Halogenation
chlorides
mesitylene
Xylenes
Column chromatography
chromatography
flash
Chromatography
Chemical activation
activation
thionyl chloride

Keywords

  • Chlorination
  • Iridium mesityl
  • Phebox ligand
  • Pincer complex
  • Thionyl chloride

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Chlorination of (Phebox)Ir(mesityl)(OAc) by thionyl chloride. / Zhou, Meng; Goldman, Alan S.

In: Molecules, Vol. 20, No. 6, 01.06.2015, p. 10122-10130.

Research output: Contribution to journalArticle

Zhou, Meng ; Goldman, Alan S. / Chlorination of (Phebox)Ir(mesityl)(OAc) by thionyl chloride. In: Molecules. 2015 ; Vol. 20, No. 6. pp. 10122-10130.
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