Contraction and Expansion of Stimuli-Responsive DNA Bonds in Flexible Colloidal Crystals

Jarad A. Mason, Christine R. Laramy, Cheng Tsung Lai, Matthew N. O'Brien, Qing Yuan Lin, Vinayak P. Dravid, George C. Schatz, Chad A. Mirkin

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

DNA surface ligands can be used as programmable "bonds" to control the arrangement of nanoparticles into crystalline superlattices. Here, we study the intrinsic responsiveness of these DNA bonds to changes in local dielectric constant (ϵr) as a new approach to dynamically modulate superlattice structure. Remarkably, ethanol (EtOH) addition can be used to controllably tune DNA bond length from 16 to 3 nm and to increase bond stability by >40 °C, while retaining long-range order and crystal habit. Interestingly, we find that these structural changes, which involve the expansion and contraction of crystals by up to 75% in volume, occur in a cooperative fashion once a critical percentage of EtOH is reached. These results provide a facile and robust approach to create stimuli-responsive lattices, to access high volume fractions, and to improve thermal stability.

Original languageEnglish
Pages (from-to)8722-8725
Number of pages4
JournalJournal of the American Chemical Society
Volume138
Issue number28
DOIs
Publication statusPublished - Jul 20 2016

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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    Mason, J. A., Laramy, C. R., Lai, C. T., O'Brien, M. N., Lin, Q. Y., Dravid, V. P., Schatz, G. C., & Mirkin, C. A. (2016). Contraction and Expansion of Stimuli-Responsive DNA Bonds in Flexible Colloidal Crystals. Journal of the American Chemical Society, 138(28), 8722-8725. https://doi.org/10.1021/jacs.6b05430