Control of electron transfer in nitrogenase

Lance C. Seefeldt, John W. Peters, David N. Beratan, Brian Bothner, Shelley D. Minteer, Simone Raugei, Brian M. Hoffman

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

The bacterial enzyme nitrogenase achieves the reduction of dinitrogen (N 2 ) to ammonia (NH 3 ) utilizing electrons, protons, and energy from the hydrolysis of ATP. Building on earlier foundational knowledge, recent studies provide molecular-level details on how the energy of ATP hydrolysis is utilized, the sequencing of multiple electron transfer events, and the nature of energy transduction across this large protein complex. Here, we review the state of knowledge about energy transduction in nitrogenase.

Original languageEnglish
Pages (from-to)54-59
Number of pages6
JournalCurrent Opinion in Chemical Biology
Volume47
DOIs
Publication statusPublished - Dec 2018

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry

Cite this

Seefeldt, L. C., Peters, J. W., Beratan, D. N., Bothner, B., Minteer, S. D., Raugei, S., & Hoffman, B. M. (2018). Control of electron transfer in nitrogenase. Current Opinion in Chemical Biology, 47, 54-59. https://doi.org/10.1016/j.cbpa.2018.08.011