Control of electron transfer in nitrogenase

Lance C. Seefeldt; John W. Peters; David N. Beratan; Brian Bothner; Shelley D. Minteer; Simone Raugei; Brian M. Hoffman

doi:10.1016/j.cbpa.2018.08.011

Control of electron transfer in nitrogenase

Lance C. Seefeldt, John W. Peters, David N. Beratan, Brian Bothner, Shelley D. Minteer, Simone Raugei, Brian M. Hoffman

Pacific Northwest National Laboratory

Research output: Contribution to journal › Review article

9 Citations (Scopus)

Abstract

The bacterial enzyme nitrogenase achieves the reduction of dinitrogen (N ₂ ) to ammonia (NH ₃ ) utilizing electrons, protons, and energy from the hydrolysis of ATP. Building on earlier foundational knowledge, recent studies provide molecular-level details on how the energy of ATP hydrolysis is utilized, the sequencing of multiple electron transfer events, and the nature of energy transduction across this large protein complex. Here, we review the state of knowledge about energy transduction in nitrogenase.

Original language	English
Pages (from-to)	54-59
Number of pages	6
Journal	Current Opinion in Chemical Biology
Volume	47
DOIs	https://doi.org/10.1016/j.cbpa.2018.08.011
Publication status	Published - Dec 2018

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ASJC Scopus subject areas

Analytical Chemistry
Biochemistry

Cite this

Seefeldt, L. C., Peters, J. W., Beratan, D. N., Bothner, B., Minteer, S. D., Raugei, S., & Hoffman, B. M. (2018). Control of electron transfer in nitrogenase. Current Opinion in Chemical Biology, 47, 54-59. https://doi.org/10.1016/j.cbpa.2018.08.011

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Access to Document

10.1016/j.cbpa.2018.08.011