Control of electron transfer in nitrogenase

Lance C. Seefeldt, John W. Peters, David N. Beratan, Brian Bothner, Shelley D. Minteer, Simone Raugei, Brian M. Hoffman

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

The bacterial enzyme nitrogenase achieves the reduction of dinitrogen (N2) to ammonia (NH3) utilizing electrons, protons, and energy from the hydrolysis of ATP. Building on earlier foundational knowledge, recent studies provide molecular-level details on how the energy of ATP hydrolysis is utilized, the sequencing of multiple electron transfer events, and the nature of energy transduction across this large protein complex. Here, we review the state of knowledge about energy transduction in nitrogenase.

Original languageEnglish
Pages (from-to)54-59
Number of pages6
JournalCurrent Opinion in Chemical Biology
Volume47
DOIs
Publication statusPublished - Dec 1 2018

Fingerprint

Nitrogenase
Hydrolysis
Adenosine Triphosphate
Electrons
Ammonia
Protons
Enzymes
Proteins

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry

Cite this

Seefeldt, L. C., Peters, J. W., Beratan, D. N., Bothner, B., Minteer, S. D., Raugei, S., & Hoffman, B. M. (2018). Control of electron transfer in nitrogenase. Current Opinion in Chemical Biology, 47, 54-59. https://doi.org/10.1016/j.cbpa.2018.08.011

Control of electron transfer in nitrogenase. / Seefeldt, Lance C.; Peters, John W.; Beratan, David N.; Bothner, Brian; Minteer, Shelley D.; Raugei, Simone; Hoffman, Brian M.

In: Current Opinion in Chemical Biology, Vol. 47, 01.12.2018, p. 54-59.

Research output: Contribution to journalReview article

Seefeldt, LC, Peters, JW, Beratan, DN, Bothner, B, Minteer, SD, Raugei, S & Hoffman, BM 2018, 'Control of electron transfer in nitrogenase', Current Opinion in Chemical Biology, vol. 47, pp. 54-59. https://doi.org/10.1016/j.cbpa.2018.08.011
Seefeldt LC, Peters JW, Beratan DN, Bothner B, Minteer SD, Raugei S et al. Control of electron transfer in nitrogenase. Current Opinion in Chemical Biology. 2018 Dec 1;47:54-59. https://doi.org/10.1016/j.cbpa.2018.08.011
Seefeldt, Lance C. ; Peters, John W. ; Beratan, David N. ; Bothner, Brian ; Minteer, Shelley D. ; Raugei, Simone ; Hoffman, Brian M. / Control of electron transfer in nitrogenase. In: Current Opinion in Chemical Biology. 2018 ; Vol. 47. pp. 54-59.
@article{f42061daffe44e26a0ff721bb8367305,
title = "Control of electron transfer in nitrogenase",
abstract = "The bacterial enzyme nitrogenase achieves the reduction of dinitrogen (N2) to ammonia (NH3) utilizing electrons, protons, and energy from the hydrolysis of ATP. Building on earlier foundational knowledge, recent studies provide molecular-level details on how the energy of ATP hydrolysis is utilized, the sequencing of multiple electron transfer events, and the nature of energy transduction across this large protein complex. Here, we review the state of knowledge about energy transduction in nitrogenase.",
author = "Seefeldt, {Lance C.} and Peters, {John W.} and Beratan, {David N.} and Brian Bothner and Minteer, {Shelley D.} and Simone Raugei and Hoffman, {Brian M.}",
year = "2018",
month = "12",
day = "1",
doi = "10.1016/j.cbpa.2018.08.011",
language = "English",
volume = "47",
pages = "54--59",
journal = "Current Opinion in Chemical Biology",
issn = "1367-5931",
publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Control of electron transfer in nitrogenase

AU - Seefeldt, Lance C.

AU - Peters, John W.

AU - Beratan, David N.

AU - Bothner, Brian

AU - Minteer, Shelley D.

AU - Raugei, Simone

AU - Hoffman, Brian M.

PY - 2018/12/1

Y1 - 2018/12/1

N2 - The bacterial enzyme nitrogenase achieves the reduction of dinitrogen (N2) to ammonia (NH3) utilizing electrons, protons, and energy from the hydrolysis of ATP. Building on earlier foundational knowledge, recent studies provide molecular-level details on how the energy of ATP hydrolysis is utilized, the sequencing of multiple electron transfer events, and the nature of energy transduction across this large protein complex. Here, we review the state of knowledge about energy transduction in nitrogenase.

AB - The bacterial enzyme nitrogenase achieves the reduction of dinitrogen (N2) to ammonia (NH3) utilizing electrons, protons, and energy from the hydrolysis of ATP. Building on earlier foundational knowledge, recent studies provide molecular-level details on how the energy of ATP hydrolysis is utilized, the sequencing of multiple electron transfer events, and the nature of energy transduction across this large protein complex. Here, we review the state of knowledge about energy transduction in nitrogenase.

UR - http://www.scopus.com/inward/record.url?scp=85052913538&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85052913538&partnerID=8YFLogxK

U2 - 10.1016/j.cbpa.2018.08.011

DO - 10.1016/j.cbpa.2018.08.011

M3 - Review article

C2 - 30205289

AN - SCOPUS:85052913538

VL - 47

SP - 54

EP - 59

JO - Current Opinion in Chemical Biology

JF - Current Opinion in Chemical Biology

SN - 1367-5931

ER -