Depth-resolved structural imaging by third-harmonic generation microscopy

Dan Oron; Dvir Yelin; Eran Tal; Sefi Raz; Rachel Fachima; Yaron Silberberg

doi:10.1016/S1047-8477(03)00125-4

Depth-resolved structural imaging by third-harmonic generation microscopy

Dan Oron, Dvir Yelin, Eran Tal, Sefi Raz, Rachel Fachima, Yaron Silberberg

Weizmann Institute of Science, Israel

Research output: Contribution to journal › Article

74 Citations (Scopus)

Abstract

Third harmonic generation microscopy is shown to be a robust method for obtaining structural information on a variety of biological specimens. Its nature allows depth-resolved imaging of inhomogeneities with virtually no background from surrounding homogeneous media. With an appropriate illumination geometry, third harmonic generation microscopy is shown to be particularly suitable for imaging of biogenic crystals, enabling extraction of the crystal orientation.

Original language	English
Pages (from-to)	3-11
Number of pages	9
Journal	Journal of Structural Biology
Volume	147
Issue number	1
DOIs	https://doi.org/10.1016/S1047-8477(03)00125-4
Publication status	Published - Jul 1 2004

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Keywords

Multiphoton microscopy
Polarization microscopy
Third harmonic generation

ASJC Scopus subject areas

Structural Biology

Cite this

Oron, D., Yelin, D., Tal, E., Raz, S., Fachima, R., & Silberberg, Y. (2004). Depth-resolved structural imaging by third-harmonic generation microscopy. Journal of Structural Biology, 147(1), 3-11. https://doi.org/10.1016/S1047-8477(03)00125-4

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10.1016/S1047-8477(03)00125-4