Design and Synthesis of a Water-Stable Anionic Uranium-Based Metal–Organic Framework (MOF) with Ultra Large Pores

Peng Li, Nicolaas A. Vermeulen, Xirui Gong, Christos D. Malliakas, J. Fraser Stoddart, Joseph T Hupp, Omar K. Farha

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Ionic metal–organic frameworks (MOFs) are a subclass of porous materials that have the ability to incorporate different charged species in confined nanospace by ion-exchange. To date, however, very few examples combining mesoporosity and water stability have been realized in ionic MOF chemistry. Herein, we report the rational design and synthesis of a water-stable anionic mesoporous MOF based on uranium and featuring tbo-type topology. The resulting tbo MOF exhibits exceptionally large open cavities (3.9 nm) exceeding those of all known anionic MOFs. By supercritical CO2activation, a record-high Brunauer-Emmett-Teller (BET) surface area (2100 m2g−1) for actinide-based MOFs has been obtained. Most importantly, however, this new uranium-based MOF is water-stable and able to absorb positively charged ions selectively over negatively charged ones, enabling the efficient separation of organic dyes and biomolecules.

Original languageEnglish
Pages (from-to)10358-10362
Number of pages5
JournalAngewandte Chemie - International Edition
Issue number35
Publication statusPublished - 2016



  • enzyme separation
  • ion exchange
  • metal–organic frameworks
  • uranium
  • water-stable MOFs

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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