TY - JOUR
T1 - Design and synthesis of readily degradable acyloxysilane dendrimers
AU - Downing, Christopher M.
AU - Missaghi, Michael N.
AU - Kung, Mayfair C.
AU - Kung, Harold H.
N1 - Funding Information:
We thank the U.S. Department of Energy , grant DE-FG02-03ER15457 , for support for CMD though the Institute for Catalysis in Energy Processes (ICEP) at Northwestern University, and grant DE-FG02-01ER15184 for support of MNM. We thank the Integrated Molecular Structure Characterization Education and Research Center (IMSERC) at Northwestern University for NMR facilities.
PY - 2011/9/30
Y1 - 2011/9/30
N2 - Two types of dendrimers with AB2 branching, one with acyloxysilanes at the branching position (V type) and the other at the non-branching position (Y type), were synthesized using hydrosilylation with chlorosilanes followed by heterofunctional condensation with olefin-functional carboxylic acids, and examined as readily degradable template materials. The V type dendrimer was much more susceptible to ligand redistribution with chlorosilanes during preparation, whereas the Y type was less. The acyloxysilane linkages in these dendrimers could be cleaved readily by alcoholysis or hydrolysis on demand, making for suitable templates.
AB - Two types of dendrimers with AB2 branching, one with acyloxysilanes at the branching position (V type) and the other at the non-branching position (Y type), were synthesized using hydrosilylation with chlorosilanes followed by heterofunctional condensation with olefin-functional carboxylic acids, and examined as readily degradable template materials. The V type dendrimer was much more susceptible to ligand redistribution with chlorosilanes during preparation, whereas the Y type was less. The acyloxysilane linkages in these dendrimers could be cleaved readily by alcoholysis or hydrolysis on demand, making for suitable templates.
KW - Acyloxysilane
KW - Degradable dendrimer
KW - Ligand redistribution
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U2 - 10.1016/j.tet.2011.07.068
DO - 10.1016/j.tet.2011.07.068
M3 - Article
AN - SCOPUS:81155159817
VL - 67
SP - 7502
EP - 7509
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 39
ER -