Abstract
Two types of dendrimers with AB2 branching, one with acyloxysilanes at the branching position (V type) and the other at the non-branching position (Y type), were synthesized using hydrosilylation with chlorosilanes followed by heterofunctional condensation with olefin-functional carboxylic acids, and examined as readily degradable template materials. The V type dendrimer was much more susceptible to ligand redistribution with chlorosilanes during preparation, whereas the Y type was less. The acyloxysilane linkages in these dendrimers could be cleaved readily by alcoholysis or hydrolysis on demand, making for suitable templates.
Original language | English |
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Pages (from-to) | 7502-7509 |
Number of pages | 8 |
Journal | Tetrahedron |
Volume | 67 |
Issue number | 39 |
DOIs | |
Publication status | Published - Sep 30 2011 |
Keywords
- Acyloxysilane
- Degradable dendrimer
- Ligand redistribution
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry