Design of biomolecules for nanoengineered biomaterials for regenerative medicine

Alvaro Mata, Liam Palmer, Esther Tejeda-Montes, Samuel I. Stupp

Research output: Chapter in Book/Report/Conference proceedingChapter

19 Citations (Scopus)

Abstract

An important goal in the development of highly functional organic materials is to design self-assembling molecules that can reproducibly display chemical signals across length scales. Within the biomedical field, biomolecules are highly attractive candidates to serve as bioactive building blocks for the next generation of biomaterials. The peptide amphiphiles (PAs) developed by the Stupp Laboratory at Northwestern University generated a highly versatile self-assembly code to create well-defined bioactive nanofibers that have been proven to be very effective at signaling cells in vitro and in vivo. Here, we describe the basic steps necessary for synthesis and assembly of PA molecules into functional nanostructures.

Original languageEnglish
Title of host publicationNanotechnology in Regenerative Medicine
Subtitle of host publicationMethods and Protocols
EditorsMelba Navarro, Josep Planell
Pages39-49
Number of pages11
DOIs
Publication statusPublished - Jan 1 2012

Publication series

NameMethods in Molecular Biology
Volume811
ISSN (Print)1064-3745

Keywords

  • Biomaterials
  • Biomolecules
  • Peptide amphiphiles
  • Peptide synthesis
  • Regenerative medicine

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Fingerprint Dive into the research topics of 'Design of biomolecules for nanoengineered biomaterials for regenerative medicine'. Together they form a unique fingerprint.

  • Cite this

    Mata, A., Palmer, L., Tejeda-Montes, E., & Stupp, S. I. (2012). Design of biomolecules for nanoengineered biomaterials for regenerative medicine. In M. Navarro, & J. Planell (Eds.), Nanotechnology in Regenerative Medicine: Methods and Protocols (pp. 39-49). (Methods in Molecular Biology; Vol. 811). https://doi.org/10.1007/978-1-61779-388-2_3