Design of biomolecules for nanoengineered biomaterials for regenerative medicine

Alvaro Mata, Liam Palmer, Esther Tejeda-Montes, Samuel I Stupp

Research output: Chapter in Book/Report/Conference proceedingChapter

12 Citations (Scopus)

Abstract

An important goal in the development of highly functional organic materials is to design self-assembling molecules that can reproducibly display chemical signals across length scales. Within the biomedical field, biomolecules are highly attractive candidates to serve as bioactive building blocks for the next generation of biomaterials. The peptide amphiphiles (PAs) developed by the Stupp Laboratory at Northwestern University generated a highly versatile self-assembly code to create well-defined bioactive nanofibers that have been proven to be very effective at signaling cells in vitro and in vivo. Here, we describe the basic steps necessary for synthesis and assembly of PA molecules into functional nanostructures.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
Pages39-49
Number of pages11
Volume811
DOIs
Publication statusPublished - 2012

Publication series

NameMethods in Molecular Biology
Volume811
ISSN (Print)10643745

Fingerprint

Regenerative Medicine
Biocompatible Materials
Nanofibers
Peptides
Nanostructures
In Vitro Techniques

Keywords

  • Biomaterials
  • Biomolecules
  • Peptide amphiphiles
  • Peptide synthesis
  • Regenerative medicine

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Cite this

Mata, A., Palmer, L., Tejeda-Montes, E., & Stupp, S. I. (2012). Design of biomolecules for nanoengineered biomaterials for regenerative medicine. In Methods in Molecular Biology (Vol. 811, pp. 39-49). (Methods in Molecular Biology; Vol. 811). https://doi.org/10.1007/978-1-61779-388-2_3

Design of biomolecules for nanoengineered biomaterials for regenerative medicine. / Mata, Alvaro; Palmer, Liam; Tejeda-Montes, Esther; Stupp, Samuel I.

Methods in Molecular Biology. Vol. 811 2012. p. 39-49 (Methods in Molecular Biology; Vol. 811).

Research output: Chapter in Book/Report/Conference proceedingChapter

Mata, A, Palmer, L, Tejeda-Montes, E & Stupp, SI 2012, Design of biomolecules for nanoengineered biomaterials for regenerative medicine. in Methods in Molecular Biology. vol. 811, Methods in Molecular Biology, vol. 811, pp. 39-49. https://doi.org/10.1007/978-1-61779-388-2_3
Mata A, Palmer L, Tejeda-Montes E, Stupp SI. Design of biomolecules for nanoengineered biomaterials for regenerative medicine. In Methods in Molecular Biology. Vol. 811. 2012. p. 39-49. (Methods in Molecular Biology). https://doi.org/10.1007/978-1-61779-388-2_3
Mata, Alvaro ; Palmer, Liam ; Tejeda-Montes, Esther ; Stupp, Samuel I. / Design of biomolecules for nanoengineered biomaterials for regenerative medicine. Methods in Molecular Biology. Vol. 811 2012. pp. 39-49 (Methods in Molecular Biology).
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