Detoxification of a Sulfur Mustard Simulant Using a BODIPY-Functionalized Zirconium-Based Metal-Organic Framework

Ahmet Atilgan; Timur Islamoglu; Ashlee J. Howarth; Joseph T. Hupp; Omar K. Farha

doi:10.1021/acsami.7b05494

Detoxification of a Sulfur Mustard Simulant Using a BODIPY-Functionalized Zirconium-Based Metal-Organic Framework

Ahmet Atilgan, Timur Islamoglu, Ashlee J. Howarth, Joseph T. Hupp, Omar K. Farha

Northwestern University

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

Effective detoxification of chemical warfare agents is a global necessity. As a powerful photosensitizer, a halogenated BODIPY ligand is postsynthetically appended to the Zr₆ nodes of the metal-organic framework (MOF), NU-1000, to enhance singlet oxygen generation from the MOF. The BODIPY/MOF material is then used as a heterogeneous photocatalyst to produce singlet oxygen under green LED irradiation. The singlet oxygen selectively detoxifies the sulfur mustard simulant, 2-chloroethyl ethyl sulfide (CEES), to the less toxic sulfoxide derivative (2-chloroethyl ethyl sulfoxide, CEESO) with a half-life of approximately 2 min.

Original language	English
Pages (from-to)	24555-24560
Number of pages	6
Journal	ACS Applied Materials and Interfaces
Volume	9
Issue number	29
DOIs	https://doi.org/10.1021/acsami.7b05494
Publication status	Published - Jul 26 2017

Keywords

BODIPY
CEES
chemical warfare agents
heterogeneous catalysis
metal-organic framework
mustard gas
photocatalyst
singlet oxygen
sulfur mustard

ASJC Scopus subject areas

Materials Science(all)

Access to Document

10.1021/acsami.7b05494

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title = "Detoxification of a Sulfur Mustard Simulant Using a BODIPY-Functionalized Zirconium-Based Metal-Organic Framework",

abstract = "Effective detoxification of chemical warfare agents is a global necessity. As a powerful photosensitizer, a halogenated BODIPY ligand is postsynthetically appended to the Zr6 nodes of the metal-organic framework (MOF), NU-1000, to enhance singlet oxygen generation from the MOF. The BODIPY/MOF material is then used as a heterogeneous photocatalyst to produce singlet oxygen under green LED irradiation. The singlet oxygen selectively detoxifies the sulfur mustard simulant, 2-chloroethyl ethyl sulfide (CEES), to the less toxic sulfoxide derivative (2-chloroethyl ethyl sulfoxide, CEESO) with a half-life of approximately 2 min.",

keywords = "BODIPY, CEES, chemical warfare agents, heterogeneous catalysis, metal-organic framework, mustard gas, photocatalyst, singlet oxygen, sulfur mustard",

author = "Ahmet Atilgan and Timur Islamoglu and Howarth, {Ashlee J.} and Hupp, {Joseph T.} and Farha, {Omar K.}",

note = "Funding Information: The authors gratefully acknowledge support from the Army Research Office (project no. W911NF-13-1-0229). A.J.H. thanks NSERC for a postdoctoral fellowship",

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AU - Atilgan, Ahmet

AU - Islamoglu, Timur

AU - Howarth, Ashlee J.

AU - Hupp, Joseph T.

AU - Farha, Omar K.

N1 - Funding Information: The authors gratefully acknowledge support from the Army Research Office (project no. W911NF-13-1-0229). A.J.H. thanks NSERC for a postdoctoral fellowship

PY - 2017/7/26

Y1 - 2017/7/26

N2 - Effective detoxification of chemical warfare agents is a global necessity. As a powerful photosensitizer, a halogenated BODIPY ligand is postsynthetically appended to the Zr6 nodes of the metal-organic framework (MOF), NU-1000, to enhance singlet oxygen generation from the MOF. The BODIPY/MOF material is then used as a heterogeneous photocatalyst to produce singlet oxygen under green LED irradiation. The singlet oxygen selectively detoxifies the sulfur mustard simulant, 2-chloroethyl ethyl sulfide (CEES), to the less toxic sulfoxide derivative (2-chloroethyl ethyl sulfoxide, CEESO) with a half-life of approximately 2 min.

AB - Effective detoxification of chemical warfare agents is a global necessity. As a powerful photosensitizer, a halogenated BODIPY ligand is postsynthetically appended to the Zr6 nodes of the metal-organic framework (MOF), NU-1000, to enhance singlet oxygen generation from the MOF. The BODIPY/MOF material is then used as a heterogeneous photocatalyst to produce singlet oxygen under green LED irradiation. The singlet oxygen selectively detoxifies the sulfur mustard simulant, 2-chloroethyl ethyl sulfide (CEES), to the less toxic sulfoxide derivative (2-chloroethyl ethyl sulfoxide, CEESO) with a half-life of approximately 2 min.

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