TY - JOUR
T1 - Detoxification of Chemical Warfare Agents Using a Zr6-Based Metal–Organic Framework/Polymer Mixture
AU - Moon, Su Young
AU - Proussaloglou, Emmanuel
AU - Peterson, Gregory W.
AU - DeCoste, Jared B.
AU - Hall, Morgan G.
AU - Howarth, Ashlee J.
AU - Hupp, Joseph T.
AU - Farha, Omar K.
N1 - Funding Information:
O.K.F. and J.T.H. acknowledge funding by the Army Research Office (project no. W911NF-13-1-0229). This work made use of the J. B. Cohen X-ray Diffraction Facility supported by the MRSEC program of the National Science Foundation (DMR-1121262) at the Materials Research Center of Northwestern University. G.W.P. and J.B.D. acknowledge funding by the Defense Threat Reduction Agency (project Nos. BA07PRO104 and BA13PHM210).
PY - 2016/10/10
Y1 - 2016/10/10
N2 - Owing to their high surface area, periodic distribution of metal sites, and water stability, zirconium-based metal–organic frameworks (Zr6-MOFs) have shown promising activity for the hydrolysis of nerve agents GD and VX, as well as the simulant, dimethyl 4-nitrophenylphosphate (DMNP), in buffered solutions. A hurdle to using MOFs for this application is the current need for a buffer solution. Here the destruction of the simulant DMNP, as well as the chemical warfare agents (GD and VX) through hydrolysis using a MOF catalyst mixed with a non-volatile, water-insoluble, heterogeneous buffer is reported. The hydrolysis of the simulant and nerve agents in the presence of the heterogeneous buffer was fast and effective.
AB - Owing to their high surface area, periodic distribution of metal sites, and water stability, zirconium-based metal–organic frameworks (Zr6-MOFs) have shown promising activity for the hydrolysis of nerve agents GD and VX, as well as the simulant, dimethyl 4-nitrophenylphosphate (DMNP), in buffered solutions. A hurdle to using MOFs for this application is the current need for a buffer solution. Here the destruction of the simulant DMNP, as well as the chemical warfare agents (GD and VX) through hydrolysis using a MOF catalyst mixed with a non-volatile, water-insoluble, heterogeneous buffer is reported. The hydrolysis of the simulant and nerve agents in the presence of the heterogeneous buffer was fast and effective.
KW - heterogeneous buffer
KW - heterogeneous catalysis
KW - hydrolysis
KW - nerve agents
KW - zirconium MOF
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U2 - 10.1002/chem.201603976
DO - 10.1002/chem.201603976
M3 - Article
AN - SCOPUS:84989917190
VL - 22
SP - 14864
EP - 14868
JO - Chemistry - A European Journal
JF - Chemistry - A European Journal
SN - 0947-6539
IS - 42
ER -