Dip-pen patterning and surface assembly of peptide amphiphiles

Hongzhou Jiang, Samuel I Stupp

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

This paper presents results on controlling the surface morphology of evaporation-driven self-assembly of peptide amphiphile (PA) nanofibers by dip-pen nanolithography. These PA nanofibers, which measure only a few nanometers in diameter, can be oriented perpendicularly to the receding edge of a solution. Dragging a meniscus of PA ink with an atomic force microscope (AFM) tip creates reproducibly aligned arrays of isolated and close-packed PA nanofiber patterns on silicon substrates, utilizing surface coating of poly(ethylene glycol) to suppress the self-assembly of nanofibers on AFM tips. We also demonstrate the ability to construct double-layer patterns of differing nanofiber orientations at the same position. This result could be important in producing a complex, multilayer pattern of these peptide-based supramolecular nanostructures.

Original languageEnglish
Pages (from-to)5242-5246
Number of pages5
JournalLangmuir
Volume21
Issue number12
DOIs
Publication statusPublished - Jun 7 2005

Fingerprint

pens
Amphiphiles
Nanofibers
Peptides
peptides
assembly
Self assembly
self assembly
Microscopes
microscopes
Nanolithography
menisci
inks
Silicon
Ink
Polyethylene glycols
Surface morphology
glycols
Nanostructures
Multilayers

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Colloid and Surface Chemistry

Cite this

Dip-pen patterning and surface assembly of peptide amphiphiles. / Jiang, Hongzhou; Stupp, Samuel I.

In: Langmuir, Vol. 21, No. 12, 07.06.2005, p. 5242-5246.

Research output: Contribution to journalArticle

Jiang, Hongzhou ; Stupp, Samuel I. / Dip-pen patterning and surface assembly of peptide amphiphiles. In: Langmuir. 2005 ; Vol. 21, No. 12. pp. 5242-5246.
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