Direct observation of reductive elimination of MeX (X = Cl, Br, I) from RhIII complexes: Mechanistic insight and the importance of sterics

Moran Feller, Yael Diskin-Posner, Gregory Leitus, Linda J.W. Shimon, David Milstein

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30 Citations (Scopus)

Abstract

Rare cases of directly observed reductive elimination (RE) of methyl halides from RhIII complexes are described. Treatment of the coordinatively unsaturated complexes [(tBuPNP)Rh(CH 3)X][BF4] (1-3, X = I, Br, and Cl; tBuPNP = 2,6-bis-(di-tert-butylphosphinomethyl)pyridine) with coordinating and noncoordinating compounds results in the formation of the corresponding free methyl halides and RhI complexes. The rate increase of CH 3I and CH3Br RE in the presence of polar aprotic solvents argues in favor of an SN2 RE mechanism. However, the RE of CH 3Cl is faster in polar protic solvents, which argues in favor of a concerted C-Cl RE. The RE of methyl halides from complexes 1-3 is induced by steric factors, as treatment of the less bulky complexes [(iPrPNP) Rh(CH3)X][BF4] (19-21; X = I, Br, Cl, respectively) with coordinating compounds leads to the formation of the adducts complexes rather than RE of the methyl halides. The accumulated evidence suggests that the RE process is nonassociative.

Original languageEnglish
Pages (from-to)11040-11047
Number of pages8
JournalJournal of the American Chemical Society
Volume135
Issue number30
DOIs
Publication statusPublished - Jul 31 2013

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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