Direct Synthesis of Benzimidazoles by Dehydrogenative Coupling of Aromatic Diamines and Alcohols Catalyzed by Cobalt

Prosenjit Daw, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journal › Article

60 Citations (Scopus)

Abstract

Herein, we present the base-metal-catalyzed dehydrogenative coupling of primary alcohols and aromatic diamines to selectively form functionalized 2-substituted benzimidazoles, liberating water and hydrogen gas as the sole byproducts. The reaction is catalyzed by pincer complexes of Earth-abundant cobalt under base-free conditions.

Original languageEnglish
Pages (from-to)7456-7460
Number of pages5
JournalACS Catalysis
Volume7
Issue number11
DOIs
Publication statusPublished - Nov 3 2017

Fingerprint

Benzimidazoles
Diamines
Cobalt
Byproducts
Hydrogen
Alcohols
Gases
Metals
Earth (planet)
Water

Keywords

  • Alcohol
  • Benzimidazole
  • Cobalt
  • Dehydrogenative Coupling
  • Pincer

ASJC Scopus subject areas

  • Catalysis

Cite this

Direct Synthesis of Benzimidazoles by Dehydrogenative Coupling of Aromatic Diamines and Alcohols Catalyzed by Cobalt. / Daw, Prosenjit; Ben-David, Yehoshoa; Milstein, David.

In: ACS Catalysis, Vol. 7, No. 11, 03.11.2017, p. 7456-7460.

Research output: Contribution to journal › Article

Daw, P, Ben-David, Y & Milstein, D 2017, 'Direct Synthesis of Benzimidazoles by Dehydrogenative Coupling of Aromatic Diamines and Alcohols Catalyzed by Cobalt', ACS Catalysis, vol. 7, no. 11, pp. 7456-7460. https://doi.org/10.1021/acscatal.7b02777
Daw P, Ben-David Y, Milstein D. Direct Synthesis of Benzimidazoles by Dehydrogenative Coupling of Aromatic Diamines and Alcohols Catalyzed by Cobalt. ACS Catalysis. 2017 Nov 3;7(11):7456-7460. https://doi.org/10.1021/acscatal.7b02777
Daw, Prosenjit ; Ben-David, Yehoshoa ; Milstein, David. / Direct Synthesis of Benzimidazoles by Dehydrogenative Coupling of Aromatic Diamines and Alcohols Catalyzed by Cobalt. In: ACS Catalysis. 2017 ; Vol. 7, No. 11. pp. 7456-7460.
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