Direct Synthesis of Benzimidazoles by Dehydrogenative Coupling of Aromatic Diamines and Alcohols Catalyzed by Cobalt

Prosenjit Daw; Yehoshoa Ben-David; David Milstein

doi:10.1021/acscatal.7b02777

Direct Synthesis of Benzimidazoles by Dehydrogenative Coupling of Aromatic Diamines and Alcohols Catalyzed by Cobalt

Prosenjit Daw, Yehoshoa Ben-David, David Milstein

Weizmann Institute of Science, Israel

Research output: Contribution to journal › Article › peer-review

82 Citations (Scopus)

Abstract

Herein, we present the base-metal-catalyzed dehydrogenative coupling of primary alcohols and aromatic diamines to selectively form functionalized 2-substituted benzimidazoles, liberating water and hydrogen gas as the sole byproducts. The reaction is catalyzed by pincer complexes of Earth-abundant cobalt under base-free conditions.

Original language	English
Pages (from-to)	7456-7460
Number of pages	5
Journal	ACS Catalysis
Volume	7
Issue number	11
DOIs	https://doi.org/10.1021/acscatal.7b02777
Publication status	Published - Nov 3 2017

Keywords

Alcohol
Benzimidazole
Cobalt
Dehydrogenative Coupling
Pincer

ASJC Scopus subject areas

Catalysis

Access to Document

10.1021/acscatal.7b02777

Fingerprint Dive into the research topics of 'Direct Synthesis of Benzimidazoles by Dehydrogenative Coupling of Aromatic Diamines and Alcohols Catalyzed by Cobalt'. Together they form a unique fingerprint.

Cite this

@article{18d74ba9dbbb41ddb45019bf7fae9e68,

title = "Direct Synthesis of Benzimidazoles by Dehydrogenative Coupling of Aromatic Diamines and Alcohols Catalyzed by Cobalt",

abstract = "Herein, we present the base-metal-catalyzed dehydrogenative coupling of primary alcohols and aromatic diamines to selectively form functionalized 2-substituted benzimidazoles, liberating water and hydrogen gas as the sole byproducts. The reaction is catalyzed by pincer complexes of Earth-abundant cobalt under base-free conditions.",

keywords = "Alcohol, Benzimidazole, Cobalt, Dehydrogenative Coupling, Pincer",

author = "Prosenjit Daw and Yehoshoa Ben-David and David Milstein",

year = "2017",

month = nov,

day = "3",

doi = "10.1021/acscatal.7b02777",

language = "English",

volume = "7",

pages = "7456--7460",

journal = "ACS Catalysis",

issn = "2155-5435",

publisher = "American Chemical Society",

number = "11",

}

TY - JOUR

T1 - Direct Synthesis of Benzimidazoles by Dehydrogenative Coupling of Aromatic Diamines and Alcohols Catalyzed by Cobalt

AU - Daw, Prosenjit

AU - Ben-David, Yehoshoa

AU - Milstein, David

PY - 2017/11/3

Y1 - 2017/11/3

N2 - Herein, we present the base-metal-catalyzed dehydrogenative coupling of primary alcohols and aromatic diamines to selectively form functionalized 2-substituted benzimidazoles, liberating water and hydrogen gas as the sole byproducts. The reaction is catalyzed by pincer complexes of Earth-abundant cobalt under base-free conditions.

AB - Herein, we present the base-metal-catalyzed dehydrogenative coupling of primary alcohols and aromatic diamines to selectively form functionalized 2-substituted benzimidazoles, liberating water and hydrogen gas as the sole byproducts. The reaction is catalyzed by pincer complexes of Earth-abundant cobalt under base-free conditions.

KW - Alcohol

KW - Benzimidazole

KW - Cobalt

KW - Dehydrogenative Coupling

KW - Pincer

UR - http://www.scopus.com/inward/record.url?scp=85032802881&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85032802881&partnerID=8YFLogxK

U2 - 10.1021/acscatal.7b02777

DO - 10.1021/acscatal.7b02777

M3 - Article

AN - SCOPUS:85032802881

VL - 7

SP - 7456

EP - 7460

JO - ACS Catalysis

JF - ACS Catalysis

SN - 2155-5435

IS - 11

ER -