Direct Synthesis of Benzimidazoles by Dehydrogenative Coupling of Aromatic Diamines and Alcohols Catalyzed by Cobalt

Prosenjit Daw, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journalArticle

62 Citations (Scopus)


Herein, we present the base-metal-catalyzed dehydrogenative coupling of primary alcohols and aromatic diamines to selectively form functionalized 2-substituted benzimidazoles, liberating water and hydrogen gas as the sole byproducts. The reaction is catalyzed by pincer complexes of Earth-abundant cobalt under base-free conditions.

Original languageEnglish
Pages (from-to)7456-7460
Number of pages5
JournalACS Catalysis
Issue number11
Publication statusPublished - Nov 3 2017



  • Alcohol
  • Benzimidazole
  • Cobalt
  • Dehydrogenative Coupling
  • Pincer

ASJC Scopus subject areas

  • Catalysis

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