Abstract
"Chemical equation presented" A clean sweep: Aryl and aliphatic mines can be synthesized directly and efficiently from alcohols and amines under mild, neutral conditions with the liberation of only molecular hydrogen and water (see scheme; R=isopropyl, tert-butyl). This general, environmentally benign reaction is catalyzed by a de-aromatized ruthenium PNP pincer complex (0.2 mol%), and can proceed in toluene under an inert atmosphere or under air.
| Original language | English |
|---|---|
| Pages (from-to) | 1468-1471 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 49 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Feb 15 2010 |
Keywords
- Homogeneous catalysis
- Mines
- Pincer complexes
- Ruthenium
- Synthetic methods
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
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Cite this
Gnanaprakasam, B., Zhang, J., & Milstein, D. (2010). Direct synthesis of imines from alcohols and amines with liberation of H2. Angewandte Chemie - International Edition, 49(8), 1468-1471. https://doi.org/10.1002/anie.200907018