Abstract
"Chemical equation presented" A clean sweep: Aryl and aliphatic mines can be synthesized directly and efficiently from alcohols and amines under mild, neutral conditions with the liberation of only molecular hydrogen and water (see scheme; R=isopropyl, tert-butyl). This general, environmentally benign reaction is catalyzed by a de-aromatized ruthenium PNP pincer complex (0.2 mol%), and can proceed in toluene under an inert atmosphere or under air.
| Original language | English |
|---|---|
| Pages (from-to) | 1468-1471 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 49 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Feb 15 2010 |
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Keywords
- Homogeneous catalysis
- Mines
- Pincer complexes
- Ruthenium
- Synthetic methods
ASJC Scopus subject areas
- Chemistry(all)
- Catalysis
Cite this
Direct synthesis of imines from alcohols and amines with liberation of H2. / Gnanaprakasam, Boopathy; Zhang, Jing; Milstein, David.
In: Angewandte Chemie - International Edition, Vol. 49, No. 8, 15.02.2010, p. 1468-1471.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Direct synthesis of imines from alcohols and amines with liberation of H2
AU - Gnanaprakasam, Boopathy
AU - Zhang, Jing
AU - Milstein, David
PY - 2010/2/15
Y1 - 2010/2/15
N2 - "Chemical equation presented" A clean sweep: Aryl and aliphatic mines can be synthesized directly and efficiently from alcohols and amines under mild, neutral conditions with the liberation of only molecular hydrogen and water (see scheme; R=isopropyl, tert-butyl). This general, environmentally benign reaction is catalyzed by a de-aromatized ruthenium PNP pincer complex (0.2 mol%), and can proceed in toluene under an inert atmosphere or under air.
AB - "Chemical equation presented" A clean sweep: Aryl and aliphatic mines can be synthesized directly and efficiently from alcohols and amines under mild, neutral conditions with the liberation of only molecular hydrogen and water (see scheme; R=isopropyl, tert-butyl). This general, environmentally benign reaction is catalyzed by a de-aromatized ruthenium PNP pincer complex (0.2 mol%), and can proceed in toluene under an inert atmosphere or under air.
KW - Homogeneous catalysis
KW - Mines
KW - Pincer complexes
KW - Ruthenium
KW - Synthetic methods
UR - http://www.scopus.com/inward/record.url?scp=76649088664&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=76649088664&partnerID=8YFLogxK
U2 - 10.1002/anie.200907018
DO - 10.1002/anie.200907018
M3 - Article
VL - 49
SP - 1468
EP - 1471
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
SN - 1433-7851
IS - 8
ER -