TY - JOUR
T1 - Direct synthesis of imines from alcohols and amines with liberation of H2
AU - Gnanaprakasam, Boopathy
AU - Zhang, Jing
AU - Milstein, David
PY - 2010/2/15
Y1 - 2010/2/15
N2 - "Chemical equation presented" A clean sweep: Aryl and aliphatic mines can be synthesized directly and efficiently from alcohols and amines under mild, neutral conditions with the liberation of only molecular hydrogen and water (see scheme; R=isopropyl, tert-butyl). This general, environmentally benign reaction is catalyzed by a de-aromatized ruthenium PNP pincer complex (0.2 mol%), and can proceed in toluene under an inert atmosphere or under air.
AB - "Chemical equation presented" A clean sweep: Aryl and aliphatic mines can be synthesized directly and efficiently from alcohols and amines under mild, neutral conditions with the liberation of only molecular hydrogen and water (see scheme; R=isopropyl, tert-butyl). This general, environmentally benign reaction is catalyzed by a de-aromatized ruthenium PNP pincer complex (0.2 mol%), and can proceed in toluene under an inert atmosphere or under air.
KW - Homogeneous catalysis
KW - Mines
KW - Pincer complexes
KW - Ruthenium
KW - Synthetic methods
UR - http://www.scopus.com/inward/record.url?scp=76649088664&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=76649088664&partnerID=8YFLogxK
U2 - 10.1002/anie.200907018
DO - 10.1002/anie.200907018
M3 - Article
C2 - 20101664
AN - SCOPUS:76649088664
VL - 49
SP - 1468
EP - 1471
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
SN - 1433-7851
IS - 8
ER -