Direct synthesis of pyridines and quinolines by coupling of γ-amino-alcohols with secondary alcohols liberating H2 catalyzed by ruthenium pincer complexes

Dipankar Srimani; Yehoshoa Ben-David; David Milstein

doi:10.1039/c3cc43227k

Direct synthesis of pyridines and quinolines by coupling of γ-amino-alcohols with secondary alcohols liberating H₂ catalyzed by ruthenium pincer complexes

Dipankar Srimani, Yehoshoa Ben-David, David Milstein

Weizmann Institute of Science, Israel

Research output: Contribution to journal › Article › peer-review

112 Citations (Scopus)

Abstract

A novel, one-step synthesis of substituted pyridine- and quinoline-derivatives was achieved by acceptorless dehydrogenative coupling of γ-aminoalcohols with secondary alcohols. The reaction involves consecutive C–N and C–C bond formation, catalyzed by a bipyridyl-based ruthenium pincer complex with a base.

Original language	English
Pages (from-to)	6632-6634
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	59
DOIs	https://doi.org/10.1039/c3cc43227k
Publication status	Published - Jun 27 2013

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "A novel, one-step synthesis of substituted pyridine- and quinoline-derivatives was achieved by acceptorless dehydrogenative coupling of γ-aminoalcohols with secondary alcohols. The reaction involves consecutive C–N and C–C bond formation, catalyzed by a bipyridyl-based ruthenium pincer complex with a base.",

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AU - Milstein, David

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