Direct synthesis of pyridines and quinolines by coupling of γ-amino-alcohols with secondary alcohols liberating H2 catalyzed by ruthenium pincer complexes

Dipankar Srimani, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journal › Article

87 Citations (Scopus)

Abstract

A novel, one-step synthesis of substituted pyridine- and quinoline-derivatives was achieved by acceptorless dehydrogenative coupling of γ-aminoalcohols with secondary alcohols. The reaction involves consecutive C-N and C-C bond formation, catalyzed by a bipyridyl-based ruthenium pincer complex with a base.

Original languageEnglish
Pages (from-to)6632-6634
Number of pages3
JournalChemical Communications
Volume49
Issue number59
DOIs
Publication statusPublished - Jul 28 2013

Fingerprint

Quinolines
Amino alcohols
Amino Alcohols
Pyridines
2,2'-Dipyridyl
Ruthenium
Pyridine
Alcohols
Derivatives
pyridine
quinoline

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

Direct synthesis of pyridines and quinolines by coupling of γ-amino-alcohols with secondary alcohols liberating H2 catalyzed by ruthenium pincer complexes. / Srimani, Dipankar; Ben-David, Yehoshoa; Milstein, David.

In: Chemical Communications, Vol. 49, No. 59, 28.07.2013, p. 6632-6634.

Research output: Contribution to journal › Article

Srimani, D, Ben-David, Y & Milstein, D 2013, 'Direct synthesis of pyridines and quinolines by coupling of γ-amino-alcohols with secondary alcohols liberating H2 catalyzed by ruthenium pincer complexes', Chemical Communications, vol. 49, no. 59, pp. 6632-6634. https://doi.org/10.1039/c3cc43227k
Srimani D, Ben-David Y, Milstein D. Direct synthesis of pyridines and quinolines by coupling of γ-amino-alcohols with secondary alcohols liberating H2 catalyzed by ruthenium pincer complexes. Chemical Communications. 2013 Jul 28;49(59):6632-6634. https://doi.org/10.1039/c3cc43227k
Srimani, Dipankar ; Ben-David, Yehoshoa ; Milstein, David. / Direct synthesis of pyridines and quinolines by coupling of γ-amino-alcohols with secondary alcohols liberating H2 catalyzed by ruthenium pincer complexes. In: Chemical Communications. 2013 ; Vol. 49, No. 59. pp. 6632-6634.
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