Direct Synthesis of Pyrroles by Dehydrogenative Coupling of Diols and Amines Catalyzed by Cobalt Pincer Complexes

Prosenjit Daw, Subrata Chakraborty, Jai Anand Garg, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Herein, the first example of base-metal-catalyzed dehydrogenative coupling of diols and amines to selectively form functionalized 1,2,5-substituted pyrroles liberating water and hydrogen gas as the sole by-products is presented. The reaction is catalyzed by pincer complexes of earth-abundant cobalt.

Original languageEnglish
Pages (from-to)14373-14377
Number of pages5
JournalAngewandte Chemie - International Edition
Volume55
Issue number46
DOIs
Publication statusPublished - 2016

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Keywords

  • cobalt
  • dehydrogenative coupling
  • pincer complexes
  • pyrroles

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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