Direct Synthesis of Pyrroles by Dehydrogenative Coupling of Diols and Amines Catalyzed by Cobalt Pincer Complexes

Prosenjit Daw, Subrata Chakraborty, Jai Anand Garg, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Herein, the first example of base-metal-catalyzed dehydrogenative coupling of diols and amines to selectively form functionalized 1,2,5-substituted pyrroles liberating water and hydrogen gas as the sole by-products is presented. The reaction is catalyzed by pincer complexes of earth-abundant cobalt.

Original languageEnglish
Pages (from-to)14373-14377
Number of pages5
JournalAngewandte Chemie - International Edition
Volume55
Issue number46
DOIs
Publication statusPublished - 2016

Fingerprint

Pyrroles
Cobalt
Amines
Byproducts
Hydrogen
Gases
Metals
Earth (planet)
Water

Keywords

  • cobalt
  • dehydrogenative coupling
  • pincer complexes
  • pyrroles

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

Direct Synthesis of Pyrroles by Dehydrogenative Coupling of Diols and Amines Catalyzed by Cobalt Pincer Complexes. / Daw, Prosenjit; Chakraborty, Subrata; Garg, Jai Anand; Ben-David, Yehoshoa; Milstein, David.

In: Angewandte Chemie - International Edition, Vol. 55, No. 46, 2016, p. 14373-14377.

Research output: Contribution to journalArticle

Daw, Prosenjit ; Chakraborty, Subrata ; Garg, Jai Anand ; Ben-David, Yehoshoa ; Milstein, David. / Direct Synthesis of Pyrroles by Dehydrogenative Coupling of Diols and Amines Catalyzed by Cobalt Pincer Complexes. In: Angewandte Chemie - International Edition. 2016 ; Vol. 55, No. 46. pp. 14373-14377.
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