Dual-Function Metal-Organic Framework as a Versatile Catalyst for Detoxifying Chemical Warfare Agent Simulants

Yangyang Liu, Su Young Moon, Joseph T Hupp, Omar K. Farha

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

The nanocrystals of a porphyrin-based zirconium(IV) metal-organic framework (MOF) are used as a dual-function catalyst for the simultaneous detoxification of two chemical warfare agent simulants at room temperature. Simulants of nerve agent (such as GD, VX) and mustard gas, dimethyl 4-nitrophenyl phosphate and 2-chloroethyl ethyl sulfide, have been hydrolyzed and oxidized, respectively, to nontoxic products via a pair of pathways catalyzed by the same MOF. Phosphotriesterase-like activity of the Zr6-containing node combined with photoactivity of the porphyrin linker gives rise to a versatile MOF catalyst. In addition, bringing the MOF crystals down to the nanoregime leads to acceleration of the catalysis.

Original languageEnglish
Pages (from-to)12358-12364
Number of pages7
JournalACS Nano
Volume9
Issue number12
DOIs
Publication statusPublished - Oct 20 2015

Fingerprint

Chemical Warfare Agents
chemical warfare
Chemical warfare
Metals
catalysts
Catalysts
Porphyrins
porphyrins
metals
Phosphoric Triester Hydrolases
Mustard Gas
Detoxification
nerves
Zirconium
Nanocrystals
Catalysis
catalysis
sulfides
nanocrystals
phosphates

Keywords

  • CEES
  • chemical warfare agents
  • DMNP
  • dual function
  • GD
  • heterogeneous catalysis
  • metal-organic frameworks
  • Simulant
  • Soman
  • VX

ASJC Scopus subject areas

  • Engineering(all)
  • Materials Science(all)
  • Physics and Astronomy(all)

Cite this

Dual-Function Metal-Organic Framework as a Versatile Catalyst for Detoxifying Chemical Warfare Agent Simulants. / Liu, Yangyang; Moon, Su Young; Hupp, Joseph T; Farha, Omar K.

In: ACS Nano, Vol. 9, No. 12, 20.10.2015, p. 12358-12364.

Research output: Contribution to journalArticle

Liu, Yangyang ; Moon, Su Young ; Hupp, Joseph T ; Farha, Omar K. / Dual-Function Metal-Organic Framework as a Versatile Catalyst for Detoxifying Chemical Warfare Agent Simulants. In: ACS Nano. 2015 ; Vol. 9, No. 12. pp. 12358-12364.
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