Abstract
The nanocrystals of a porphyrin-based zirconium(IV) metal-organic framework (MOF) are used as a dual-function catalyst for the simultaneous detoxification of two chemical warfare agent simulants at room temperature. Simulants of nerve agent (such as GD, VX) and mustard gas, dimethyl 4-nitrophenyl phosphate and 2-chloroethyl ethyl sulfide, have been hydrolyzed and oxidized, respectively, to nontoxic products via a pair of pathways catalyzed by the same MOF. Phosphotriesterase-like activity of the Zr6-containing node combined with photoactivity of the porphyrin linker gives rise to a versatile MOF catalyst. In addition, bringing the MOF crystals down to the nanoregime leads to acceleration of the catalysis.
| Original language | English |
|---|---|
| Pages (from-to) | 12358-12364 |
| Number of pages | 7 |
| Journal | ACS Nano |
| Volume | 9 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Oct 20 2015 |
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Keywords
- CEES
- chemical warfare agents
- DMNP
- dual function
- GD
- heterogeneous catalysis
- metal-organic frameworks
- Simulant
- Soman
- VX
ASJC Scopus subject areas
- Engineering(all)
- Materials Science(all)
- Physics and Astronomy(all)
Cite this
Dual-Function Metal-Organic Framework as a Versatile Catalyst for Detoxifying Chemical Warfare Agent Simulants. / Liu, Yangyang; Moon, Su Young; Hupp, Joseph T; Farha, Omar K.
In: ACS Nano, Vol. 9, No. 12, 20.10.2015, p. 12358-12364.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dual-Function Metal-Organic Framework as a Versatile Catalyst for Detoxifying Chemical Warfare Agent Simulants
AU - Liu, Yangyang
AU - Moon, Su Young
AU - Hupp, Joseph T
AU - Farha, Omar K.
PY - 2015/10/20
Y1 - 2015/10/20
N2 - The nanocrystals of a porphyrin-based zirconium(IV) metal-organic framework (MOF) are used as a dual-function catalyst for the simultaneous detoxification of two chemical warfare agent simulants at room temperature. Simulants of nerve agent (such as GD, VX) and mustard gas, dimethyl 4-nitrophenyl phosphate and 2-chloroethyl ethyl sulfide, have been hydrolyzed and oxidized, respectively, to nontoxic products via a pair of pathways catalyzed by the same MOF. Phosphotriesterase-like activity of the Zr6-containing node combined with photoactivity of the porphyrin linker gives rise to a versatile MOF catalyst. In addition, bringing the MOF crystals down to the nanoregime leads to acceleration of the catalysis.
AB - The nanocrystals of a porphyrin-based zirconium(IV) metal-organic framework (MOF) are used as a dual-function catalyst for the simultaneous detoxification of two chemical warfare agent simulants at room temperature. Simulants of nerve agent (such as GD, VX) and mustard gas, dimethyl 4-nitrophenyl phosphate and 2-chloroethyl ethyl sulfide, have been hydrolyzed and oxidized, respectively, to nontoxic products via a pair of pathways catalyzed by the same MOF. Phosphotriesterase-like activity of the Zr6-containing node combined with photoactivity of the porphyrin linker gives rise to a versatile MOF catalyst. In addition, bringing the MOF crystals down to the nanoregime leads to acceleration of the catalysis.
KW - CEES
KW - chemical warfare agents
KW - DMNP
KW - dual function
KW - GD
KW - heterogeneous catalysis
KW - metal-organic frameworks
KW - Simulant
KW - Soman
KW - VX
UR - http://www.scopus.com/inward/record.url?scp=84952321472&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84952321472&partnerID=8YFLogxK
U2 - 10.1021/acsnano.5b05660
DO - 10.1021/acsnano.5b05660
M3 - Article
C2 - 26482030
AN - SCOPUS:84952321472
VL - 9
SP - 12358
EP - 12364
JO - ACS Nano
JF - ACS Nano
SN - 1936-0851
IS - 12
ER -