Dual-Function Metal-Organic Framework as a Versatile Catalyst for Detoxifying Chemical Warfare Agent Simulants

Yangyang Liu; Su Young Moon; Joseph T. Hupp; Omar K. Farha

doi:10.1021/acsnano.5b05660

Dual-Function Metal-Organic Framework as a Versatile Catalyst for Detoxifying Chemical Warfare Agent Simulants

Yangyang Liu, Su Young Moon, Joseph T. Hupp, Omar K. Farha

Northwestern University

Research output: Contribution to journal › Article › peer-review

133 Citations (Scopus)

Abstract

The nanocrystals of a porphyrin-based zirconium(IV) metal-organic framework (MOF) are used as a dual-function catalyst for the simultaneous detoxification of two chemical warfare agent simulants at room temperature. Simulants of nerve agent (such as GD, VX) and mustard gas, dimethyl 4-nitrophenyl phosphate and 2-chloroethyl ethyl sulfide, have been hydrolyzed and oxidized, respectively, to nontoxic products via a pair of pathways catalyzed by the same MOF. Phosphotriesterase-like activity of the Zr₆-containing node combined with photoactivity of the porphyrin linker gives rise to a versatile MOF catalyst. In addition, bringing the MOF crystals down to the nanoregime leads to acceleration of the catalysis.

Original language	English
Pages (from-to)	12358-12364
Number of pages	7
Journal	ACS nano
Volume	9
Issue number	12
DOIs	https://doi.org/10.1021/acsnano.5b05660
Publication status	Published - Oct 20 2015

Keywords

CEES
DMNP
GD
Simulant
Soman
VX
chemical warfare agents
dual function
heterogeneous catalysis
metal-organic frameworks

ASJC Scopus subject areas

Materials Science(all)
Engineering(all)
Physics and Astronomy(all)

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title = "Dual-Function Metal-Organic Framework as a Versatile Catalyst for Detoxifying Chemical Warfare Agent Simulants",

abstract = "The nanocrystals of a porphyrin-based zirconium(IV) metal-organic framework (MOF) are used as a dual-function catalyst for the simultaneous detoxification of two chemical warfare agent simulants at room temperature. Simulants of nerve agent (such as GD, VX) and mustard gas, dimethyl 4-nitrophenyl phosphate and 2-chloroethyl ethyl sulfide, have been hydrolyzed and oxidized, respectively, to nontoxic products via a pair of pathways catalyzed by the same MOF. Phosphotriesterase-like activity of the Zr6-containing node combined with photoactivity of the porphyrin linker gives rise to a versatile MOF catalyst. In addition, bringing the MOF crystals down to the nanoregime leads to acceleration of the catalysis.",

keywords = "CEES, DMNP, GD, Simulant, Soman, VX, chemical warfare agents, dual function, heterogeneous catalysis, metal-organic frameworks",

author = "Yangyang Liu and Moon, {Su Young} and Hupp, {Joseph T.} and Farha, {Omar K.}",

note = "Funding Information: O.K.F. and J.T.H. gratefully acknowledge DTRA for financial support (grant HDTRA-1-10-0023). This work made use of the J. B. Cohen X-ray Diffraction Facility supported by the MRSEC program of the National Science Foundation (DMR-1121262) at the Materials Research Center of Northwestern University. This work also made use of the EPIC facility (NUANCE Center-Northwestern University), which has received support from the MRSEC program (NSF DMR-1121262) at the Materials Research Center; the International Institute for Nanotechnology (IIN); and the State of Illinois, through the IIN.",

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Dual-Function Metal-Organic Framework as a Versatile Catalyst for Detoxifying Chemical Warfare Agent Simulants

Abstract

Keywords

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