Abstract
A deep hole trap is 7-deazaguanine (Z) - According to time-resolved transient absorption spectroscopy and kinetic modeling - For hole transport in DNA from a guanine (G) to a Z base across one or two intervening adenine-thymine base pairs. The Gibbs energy for hole transport from G to Z was determined to be - 0.19 eV, much larger than values for GG or GGG sites. Thus Z effectively prevents charge migration in DNA.
Original language | English |
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Pages (from-to) | 1026-1028 |
Number of pages | 3 |
Journal | Angewandte Chemie - International Edition |
Volume | 41 |
Issue number | 6 |
DOIs | |
Publication status | Published - Mar 15 2002 |
Keywords
- DNA conjugates
- Electron transfer
- Photooxidation
- Picosecond spectroscopy 1020-1022
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)