Abstract
Second harmonic generation (SHG) was used to study both the adsorption of malachite green (MG), a positively charged organic dye, onto liposomes of different lipid compositions, and the transport kinetics of MG across the liposome bilayer in real time. We found that the dye adsorption increased linearly with the fraction of negatively charged lipids in the bilayer. Similarly, the transport rate constant for crossing the bilayer increased linearly with the fraction of charged lipid in the bilayer.
| Original language | English |
|---|---|
| Pages (from-to) | 1004-1012 |
| Number of pages | 9 |
| Journal | Biophysical Journal |
| Volume | 80 |
| Issue number | 2 |
| Publication status | Published - 2001 |
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- Biophysics
Cite this
Effects of bilayer surface charge density on molecular adsorption and transport across liposome bilayers. / Liu, Yan; Yan, Elsa C Y; Eisenthal, Kenneth B.
In: Biophysical Journal, Vol. 80, No. 2, 2001, p. 1004-1012.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of bilayer surface charge density on molecular adsorption and transport across liposome bilayers
AU - Liu, Yan
AU - Yan, Elsa C Y
AU - Eisenthal, Kenneth B.
PY - 2001
Y1 - 2001
N2 - Second harmonic generation (SHG) was used to study both the adsorption of malachite green (MG), a positively charged organic dye, onto liposomes of different lipid compositions, and the transport kinetics of MG across the liposome bilayer in real time. We found that the dye adsorption increased linearly with the fraction of negatively charged lipids in the bilayer. Similarly, the transport rate constant for crossing the bilayer increased linearly with the fraction of charged lipid in the bilayer.
AB - Second harmonic generation (SHG) was used to study both the adsorption of malachite green (MG), a positively charged organic dye, onto liposomes of different lipid compositions, and the transport kinetics of MG across the liposome bilayer in real time. We found that the dye adsorption increased linearly with the fraction of negatively charged lipids in the bilayer. Similarly, the transport rate constant for crossing the bilayer increased linearly with the fraction of charged lipid in the bilayer.
UR - http://www.scopus.com/inward/record.url?scp=0035144447&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035144447&partnerID=8YFLogxK
M3 - Article
C2 - 11159467
AN - SCOPUS:0035144447
VL - 80
SP - 1004
EP - 1012
JO - Biophysical Journal
JF - Biophysical Journal
SN - 0006-3495
IS - 2
ER -