Efficient homogeneous catalytic hydrogenation of esters to alcohols

Jing Zhang; Gregory Leitus; Yehoshoa Ben-David; David Milstein

doi:10.1002/anie.200503771

Efficient homogeneous catalytic hydrogenation of esters to alcohols

Jing Zhang, Gregory Leitus, Yehoshoa Ben-David, David Milstein

Weizmann Institute of Science, Israel

Research output: Contribution to journal › Article

390 Citations (Scopus)

Abstract

(Chemical Equation Presented) With open arms: A ruthenium PNN complex (see scheme) catalyzes the hydrogenation of esters in high yields under neutral conditions. The analogous PNP complex is less active. A mechanism is proposed based on the hemilabile nature of the PNN ligand which allows a vacant site to be created by decoordination of the -CH₂NEt₂ arm.

Original language	English
Pages (from-to)	1113-1115
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	7
DOIs	https://doi.org/10.1002/anie.200503771
Publication status	Published - Feb 6 2006

Fingerprint

Keywords

Alcohols
Esters
Homogeneous catalysis
Hydrogenation
Ruthenium

ASJC Scopus subject areas

Catalysis
Chemistry(all)

Cite this

Zhang, J., Leitus, G., Ben-David, Y., & Milstein, D. (2006). Efficient homogeneous catalytic hydrogenation of esters to alcohols. Angewandte Chemie - International Edition, 45(7), 1113-1115. https://doi.org/10.1002/anie.200503771

@article{a997f35dd42a4f10a94e9c5419d2d3a2,

title = "Efficient homogeneous catalytic hydrogenation of esters to alcohols",

abstract = "(Chemical Equation Presented) With open arms: A ruthenium PNN complex (see scheme) catalyzes the hydrogenation of esters in high yields under neutral conditions. The analogous PNP complex is less active. A mechanism is proposed based on the hemilabile nature of the PNN ligand which allows a vacant site to be created by decoordination of the -CH2NEt2 arm.",

keywords = "Alcohols, Esters, Homogeneous catalysis, Hydrogenation, Ruthenium",

author = "Jing Zhang and Gregory Leitus and Yehoshoa Ben-David and David Milstein",

year = "2006",

month = feb,

day = "6",

doi = "10.1002/anie.200503771",

language = "English",

volume = "45",

pages = "1113--1115",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "7",

}

TY - JOUR

T1 - Efficient homogeneous catalytic hydrogenation of esters to alcohols

AU - Zhang, Jing

AU - Leitus, Gregory

AU - Ben-David, Yehoshoa

AU - Milstein, David

PY - 2006/2/6

Y1 - 2006/2/6

N2 - (Chemical Equation Presented) With open arms: A ruthenium PNN complex (see scheme) catalyzes the hydrogenation of esters in high yields under neutral conditions. The analogous PNP complex is less active. A mechanism is proposed based on the hemilabile nature of the PNN ligand which allows a vacant site to be created by decoordination of the -CH2NEt2 arm.

AB - (Chemical Equation Presented) With open arms: A ruthenium PNN complex (see scheme) catalyzes the hydrogenation of esters in high yields under neutral conditions. The analogous PNP complex is less active. A mechanism is proposed based on the hemilabile nature of the PNN ligand which allows a vacant site to be created by decoordination of the -CH2NEt2 arm.

KW - Alcohols

KW - Esters

KW - Homogeneous catalysis

KW - Hydrogenation

KW - Ruthenium

UR - http://www.scopus.com/inward/record.url?scp=33744455063&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33744455063&partnerID=8YFLogxK

U2 - 10.1002/anie.200503771

DO - 10.1002/anie.200503771

M3 - Article

C2 - 16389607

AN - SCOPUS:33744455063

VL - 45

SP - 1113

EP - 1115

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

SN - 1433-7851

IS - 7

ER -

Access to Document

10.1002/anie.200503771