Efficient homogeneous catalytic hydrogenation of esters to alcohols

Jing Zhang, Gregory Leitus, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journalArticle

391 Citations (Scopus)

Abstract

(Chemical Equation Presented) With open arms: A ruthenium PNN complex (see scheme) catalyzes the hydrogenation of esters in high yields under neutral conditions. The analogous PNP complex is less active. A mechanism is proposed based on the hemilabile nature of the PNN ligand which allows a vacant site to be created by decoordination of the -CH2NEt2 arm.

Original languageEnglish
Pages (from-to)1113-1115
Number of pages3
JournalAngewandte Chemie - International Edition
Volume45
Issue number7
DOIs
Publication statusPublished - Feb 6 2006

Keywords

  • Alcohols
  • Esters
  • Homogeneous catalysis
  • Hydrogenation
  • Ruthenium

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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