Efficient hydrogenation of ketones catalyzed by an iron pincer complex

Robert Langer, Gregory Leitus, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journalArticle

255 Citations (Scopus)

Abstract

Reductions made easy: A highly efficient iron catalyst effects the homogeneous hydrogenation of ketones under very mild conditions (see scheme). A mechanism including the insertion of the ketone into the Fei-H bond, followed by addition of hydrogen to a dearomatized intermediate is proposed.

Original languageEnglish
Pages (from-to)2120-2124
Number of pages5
JournalAngewandte Chemie - International Edition
Volume50
Issue number9
DOIs
Publication statusPublished - Feb 25 2011

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Ketones
Hydrogenation
Iron
Hydrogen
Catalysts

Keywords

  • homogeneous catalysis
  • hydrogenation
  • iron complexes
  • ketones
  • pincer ligands

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

Cite this

Efficient hydrogenation of ketones catalyzed by an iron pincer complex. / Langer, Robert; Leitus, Gregory; Ben-David, Yehoshoa; Milstein, David.

In: Angewandte Chemie - International Edition, Vol. 50, No. 9, 25.02.2011, p. 2120-2124.

Research output: Contribution to journalArticle

Langer, Robert ; Leitus, Gregory ; Ben-David, Yehoshoa ; Milstein, David. / Efficient hydrogenation of ketones catalyzed by an iron pincer complex. In: Angewandte Chemie - International Edition. 2011 ; Vol. 50, No. 9. pp. 2120-2124.
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