Efficient hydrogenation of ketones catalyzed by an iron pincer complex

Robert Langer, Gregory Leitus, Yehoshoa Ben-David, David Milstein

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264 Citations (Scopus)

Abstract

Reductions made easy: A highly efficient iron catalyst effects the homogeneous hydrogenation of ketones under very mild conditions (see scheme). A mechanism including the insertion of the ketone into the Fei-H bond, followed by addition of hydrogen to a dearomatized intermediate is proposed.

Original languageEnglish
Pages (from-to)2120-2124
Number of pages5
JournalAngewandte Chemie - International Edition
Volume50
Issue number9
DOIs
Publication statusPublished - Feb 25 2011

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Keywords

  • homogeneous catalysis
  • hydrogenation
  • iron complexes
  • ketones
  • pincer ligands

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

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