Efficient intramolecular hydroalkoxylation/cyclization of unactivated alkenols mediated by lanthanide triflate ionic liquids

Alma Dzudza, Tobin J Marks

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Lanthanide triflates, Ln(OTf) 3, serve as efficient catalysts for the intramolecular hydroalkoxylation (HO)/cyclization of primary/secondary and aliphatic/aromatic hydroxyalkenes in room temperature ionic liquids (RTlLs). Cyclizations are effective in the formation of five-and sixmembered oxygen heterocycles with Markovnikov-type selectivity. Reaction rates exhibit first-order dependence on [Ln 3+] and [substrate].

Original languageEnglish
Pages (from-to)1523-1526
Number of pages4
JournalOrganic Letters
Volume11
Issue number7
DOIs
Publication statusPublished - Apr 2 2009

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Ionic Liquids
Lanthanoid Series Elements
Cyclization
reaction kinetics
selectivity
catalysts
Catalyst selectivity
room temperature
oxygen
liquids
Reaction rates
Oxygen
Catalysts
Temperature
Substrates

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Efficient intramolecular hydroalkoxylation/cyclization of unactivated alkenols mediated by lanthanide triflate ionic liquids. / Dzudza, Alma; Marks, Tobin J.

In: Organic Letters, Vol. 11, No. 7, 02.04.2009, p. 1523-1526.

Research output: Contribution to journalArticle

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