Abstract
Platinum or gold electrodes derivatized with an N,N′-dialkyl-4, 4′-bipyridinium reagent can be used to reduce horse heart ferricytochrome c, whereas reduction does not occur at the "naked" electrodes. From 3 to 17.7 millimoles per liter, the reduction of ferricytochrome c is mass transport-limited at electrode potentials more negative than about -0.6 volt against a saturated calomel reference electrode. Data for the photoreduction of ferricytochrome c at derivatized p-type silicon photocathodes show directly that the rate of reduction is mass transport-limited. Use of derivatized electrodes may allow convenient manipulation and analysis of biological molecules that do not ordinarily respond at conventional electrodes.
| Original language | English |
|---|---|
| Pages (from-to) | 944-947 |
| Number of pages | 4 |
| Journal | Science |
| Volume | 211 |
| Issue number | 4485 |
| Publication status | Published - 1981 |
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Cite this
Electrochemical reduction of horse heart ferricytochrome c at chemically derivatized electrodes. / Lewis, Nathan S; Wrighton, Mark S.
In: Science, Vol. 211, No. 4485, 1981, p. 944-947.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Electrochemical reduction of horse heart ferricytochrome c at chemically derivatized electrodes
AU - Lewis, Nathan S
AU - Wrighton, Mark S.
PY - 1981
Y1 - 1981
N2 - Platinum or gold electrodes derivatized with an N,N′-dialkyl-4, 4′-bipyridinium reagent can be used to reduce horse heart ferricytochrome c, whereas reduction does not occur at the "naked" electrodes. From 3 to 17.7 millimoles per liter, the reduction of ferricytochrome c is mass transport-limited at electrode potentials more negative than about -0.6 volt against a saturated calomel reference electrode. Data for the photoreduction of ferricytochrome c at derivatized p-type silicon photocathodes show directly that the rate of reduction is mass transport-limited. Use of derivatized electrodes may allow convenient manipulation and analysis of biological molecules that do not ordinarily respond at conventional electrodes.
AB - Platinum or gold electrodes derivatized with an N,N′-dialkyl-4, 4′-bipyridinium reagent can be used to reduce horse heart ferricytochrome c, whereas reduction does not occur at the "naked" electrodes. From 3 to 17.7 millimoles per liter, the reduction of ferricytochrome c is mass transport-limited at electrode potentials more negative than about -0.6 volt against a saturated calomel reference electrode. Data for the photoreduction of ferricytochrome c at derivatized p-type silicon photocathodes show directly that the rate of reduction is mass transport-limited. Use of derivatized electrodes may allow convenient manipulation and analysis of biological molecules that do not ordinarily respond at conventional electrodes.
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M3 - Article
VL - 211
SP - 944
EP - 947
JO - Science
JF - Science
SN - 0036-8075
IS - 4485
ER -