Electrophilic activation of hydrogen peroxide: Selective oxidation reactions in perfluorinated alcohol solvents

Karine Neimann, Ronny Neumann

Research output: Contribution to journalArticle

122 Citations (Scopus)

Abstract

The catalytic electrophilic activation of hydrogen peroxide with transition metal compounds toward reaction with nucleophiles is a matter of very significant research and practical interest. We have now found that use of perfluorinated alcoholic solvents such as 1,1,1,3,3,3-hexafluoro-2-propanol in the absence of catalysts allowed electrophilic activation of hydrogen peroxide toward epoxidation of alkenes and the Baeyer-Villiger oxidation of ketones.

Original languageEnglish
Pages (from-to)2861-2863
Number of pages3
JournalOrganic Letters
Volume2
Issue number18
Publication statusPublished - Sep 7 2000

Fingerprint

hydrogen peroxide
Hydrogen Peroxide
alcohols
Chemical activation
Alcohols
activation
Transition metal compounds
Oxidation
Nucleophiles
oxidation
epoxidation
Epoxidation
metal compounds
nucleophiles
Alkenes
Ketones
ketones
alkenes
Metals
transition metals

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Electrophilic activation of hydrogen peroxide : Selective oxidation reactions in perfluorinated alcohol solvents. / Neimann, Karine; Neumann, Ronny.

In: Organic Letters, Vol. 2, No. 18, 07.09.2000, p. 2861-2863.

Research output: Contribution to journalArticle

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