Electrospinning bioactive supramolecular polymers from water

Alok S. Tayi, E. Thomas Pashuck, Christina J. Newcomb, Mark T. McClendon, Samuel I. Stupp

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Electrospinning is a high-throughput, low-cost technique for manufacturing long fibers from solution. Conventionally, this technique is used with covalent polymers with large molecular weights. We report here the electrospinning of functional peptide-based supramolecular polymers from water at very low concentrations (<4 wt %). Molecules with low molecular weights (<1 kDa) could be electrospun because they self-assembled into one-dimensional supramolecular polymers upon solvation and the critical parameters of viscosity, solution conductivity, and surface tension were optimized for this technique. The supramolecular structure of the electrospun fibers could ensure that certain residues, like bioepitopes, are displayed on the surface even after processing. This system provides an opportunity to electrospin bioactive supramolecular materials from water for biomedical applications.

Original languageEnglish
Pages (from-to)1323-1327
Number of pages5
JournalBiomacromolecules
Volume15
Issue number4
DOIs
Publication statusPublished - Apr 14 2014

ASJC Scopus subject areas

  • Bioengineering
  • Biomaterials
  • Polymers and Plastics
  • Materials Chemistry

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  • Cite this

    Tayi, A. S., Pashuck, E. T., Newcomb, C. J., McClendon, M. T., & Stupp, S. I. (2014). Electrospinning bioactive supramolecular polymers from water. Biomacromolecules, 15(4), 1323-1327. https://doi.org/10.1021/bm401877s