Encapsulation of gold nanoparticles in a DNA origami cage

Zhao Zhao, Erica L. Jacovetty, Yan Liu, Hao Yan

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

Fold and label: A critical challenge in nanoparticle (NP) surface functionalization is to label the NP surface with a single copy of a functional group or to display multiple, unique molecules on the NP surface with control of the orientation and intermolecular distance. This challenge was addressed with the construction of a spatially addressable, self-assembling DNA origami nanocage that encapsulates gold nanoparticles and interrupts its surface symmetry (see scheme).

Original languageEnglish
Pages (from-to)2041-2044
Number of pages4
JournalAngewandte Chemie - International Edition
Volume50
Issue number9
DOIs
Publication statusPublished - Feb 25 2011

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Encapsulation
Gold
DNA
Nanoparticles
Labels
Functional groups
Molecules

Keywords

  • DNA
  • gold
  • nanoparticles
  • nanotechnology

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

Cite this

Encapsulation of gold nanoparticles in a DNA origami cage. / Zhao, Zhao; Jacovetty, Erica L.; Liu, Yan; Yan, Hao.

In: Angewandte Chemie - International Edition, Vol. 50, No. 9, 25.02.2011, p. 2041-2044.

Research output: Contribution to journalArticle

Zhao, Zhao ; Jacovetty, Erica L. ; Liu, Yan ; Yan, Hao. / Encapsulation of gold nanoparticles in a DNA origami cage. In: Angewandte Chemie - International Edition. 2011 ; Vol. 50, No. 9. pp. 2041-2044.
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