Enzymic regioselectivity in the hydroxylation of cholesterol catalyzed by a membrane-spanning metalloporphyrin

John T. Groves; Ronny Neumann

Enzymic regioselectivity in the hydroxylation of cholesterol catalyzed by a membrane-spanning metalloporphyrin

John T. Groves, Ronny Neumann

Weizmann Institute of Science, Israel

Research output: Contribution to journal › Article › peer-review

58 Citations (Scopus)

Abstract

The hydroxylation of simple alkanes and the selective C-25 hydroxylation of cholesterol have been achieved with a membrane-spanning Mn(III) porphyrin positioned in a synthetic bilayer assembly by appended steroidal substituents.

Original language	English
Pages (from-to)	3891-3893
Number of pages	3
Journal	Journal of Organic Chemistry
Volume	53
Issue number	16
Publication status	Published - 1988

ASJC Scopus subject areas

Organic Chemistry

Fingerprint Dive into the research topics of 'Enzymic regioselectivity in the hydroxylation of cholesterol catalyzed by a membrane-spanning metalloporphyrin'. Together they form a unique fingerprint.

Cite this

@article{37f66b69643241ca8bf17cc6398d8c7e,

title = "Enzymic regioselectivity in the hydroxylation of cholesterol catalyzed by a membrane-spanning metalloporphyrin",

abstract = "The hydroxylation of simple alkanes and the selective C-25 hydroxylation of cholesterol have been achieved with a membrane-spanning Mn(III) porphyrin positioned in a synthetic bilayer assembly by appended steroidal substituents.",

author = "Groves, {John T.} and Ronny Neumann",

year = "1988",

language = "English",

volume = "53",

pages = "3891--3893",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "16",

}

TY - JOUR

T1 - Enzymic regioselectivity in the hydroxylation of cholesterol catalyzed by a membrane-spanning metalloporphyrin

AU - Groves, John T.

AU - Neumann, Ronny

PY - 1988

Y1 - 1988

N2 - The hydroxylation of simple alkanes and the selective C-25 hydroxylation of cholesterol have been achieved with a membrane-spanning Mn(III) porphyrin positioned in a synthetic bilayer assembly by appended steroidal substituents.

AB - The hydroxylation of simple alkanes and the selective C-25 hydroxylation of cholesterol have been achieved with a membrane-spanning Mn(III) porphyrin positioned in a synthetic bilayer assembly by appended steroidal substituents.

UR - http://www.scopus.com/inward/record.url?scp=33845280792&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33845280792&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33845280792

VL - 53

SP - 3891

EP - 3893

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

SN - 0022-3263

IS - 16

ER -