Abstract
Getting heavy: At temperatures as low as 50°C, D2O can serve as a cheap and readily available deuterium source for the efficient deuteration of aromatic and heteroaromatic substrates if nonclassical ruthenium hydride complexes are used as catalysts (see scheme). DFT calculations support a catalytic cycle comprising σ-bond metathesis as the key step for the exchange processes. (Chemical Equation Presented).
Original language | English |
---|---|
Pages (from-to) | 2269-2272 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 46 |
Issue number | 13 |
DOIs | |
Publication status | Published - 2007 |
Keywords
- C-H activation
- Density functional calculations
- H/D exchange
- Homogeneous catalysis
- Ruthenium
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)