Abstract
We report the heterogeneously catalyzed hydrogenation of amides to form alcohols and amines. This C-N bond cleavage reaction is catalyzed by silver on γ-alumina, proceeds smoothly in high yields and 100% selectivity, and is effective for both benzamides and aliphatic amides. This is in contrast to amide hydrogenation catalyzed by heterogeneous catalysts, which generally proceeds via C-O bond cleavage. Recycling experiments show that the catalyst Ag/γ-Al2O3 can be easily recovered and regenerated without decrease in catalytic activity.
| Original language | English |
|---|---|
| Pages (from-to) | 2784-2788 |
| Number of pages | 5 |
| Journal | Catalysis Science and Technology |
| Volume | 8 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Jan 1 2018 |
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ASJC Scopus subject areas
- Catalysis
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Heterogeneously catalyzed selective hydrogenation of amides to alcohols and amines. / Xie, Yinjun; Hu, Peng; Bendikov, Tatyana; Milstein, David.
In: Catalysis Science and Technology, Vol. 8, No. 11, 01.01.2018, p. 2784-2788.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Heterogeneously catalyzed selective hydrogenation of amides to alcohols and amines
AU - Xie, Yinjun
AU - Hu, Peng
AU - Bendikov, Tatyana
AU - Milstein, David
PY - 2018/1/1
Y1 - 2018/1/1
N2 - We report the heterogeneously catalyzed hydrogenation of amides to form alcohols and amines. This C-N bond cleavage reaction is catalyzed by silver on γ-alumina, proceeds smoothly in high yields and 100% selectivity, and is effective for both benzamides and aliphatic amides. This is in contrast to amide hydrogenation catalyzed by heterogeneous catalysts, which generally proceeds via C-O bond cleavage. Recycling experiments show that the catalyst Ag/γ-Al2O3 can be easily recovered and regenerated without decrease in catalytic activity.
AB - We report the heterogeneously catalyzed hydrogenation of amides to form alcohols and amines. This C-N bond cleavage reaction is catalyzed by silver on γ-alumina, proceeds smoothly in high yields and 100% selectivity, and is effective for both benzamides and aliphatic amides. This is in contrast to amide hydrogenation catalyzed by heterogeneous catalysts, which generally proceeds via C-O bond cleavage. Recycling experiments show that the catalyst Ag/γ-Al2O3 can be easily recovered and regenerated without decrease in catalytic activity.
UR - http://www.scopus.com/inward/record.url?scp=85048414110&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85048414110&partnerID=8YFLogxK
U2 - 10.1039/c8cy00112j
DO - 10.1039/c8cy00112j
M3 - Article
AN - SCOPUS:85048414110
VL - 8
SP - 2784
EP - 2788
JO - Catalysis Science and Technology
JF - Catalysis Science and Technology
SN - 2044-4753
IS - 11
ER -