High spatial resolution imaging with near-field scanning optical microscopy in liquids

L. F. Lee, R. D. Schaller, L. H. Haber, R. J. Saykally

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20 Citations (Scopus)


The mechanism of tuning fork-based shear-force near-field scanning optical microscopy is investigated to determine optimal experimental conditions for imaging soft samples immersed in liquid. High feedback sensitivity and stability are obtained when only the fiber probe, i.e., excluding the tuning fork prongs, is immersed in solution, which also avoids electrical shorting in conductive (i.e., buffer) solutions. Images of MEH-PPV were obtained with comparable spatial resolution in both air and water. High optical resolution (∼160 nm fwhm) was observed.

Original languageEnglish
Pages (from-to)5015-5019
Number of pages5
JournalAnalytical Chemistry
Issue number21
Publication statusPublished - Nov 1 2001


ASJC Scopus subject areas

  • Analytical Chemistry

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