Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal-Ligand Cooperation

You Quan Zou, Subrata Chakraborty, Alexander Nerush, Dror Oren, Yael Diskin-Posner, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Deoxygenative hydrogenation of amides to amines homogeneously catalyzed by a complex of an Earth-abundant metal is presented. This manganese-catalyzed reaction features high efficiency and selectivity. A plausible reaction mechanism, involving metal-ligand cooperation of the manganese pincer complex, is proposed based on NMR studies and relevant stoichiometric reactions.

Original languageEnglish
Pages (from-to)8014-8019
Number of pages6
JournalACS Catalysis
Volume8
Issue number9
DOIs
Publication statusPublished - Sep 7 2018

Fingerprint

Manganese
Amides
Hydrogenation
Metals
Ligands
Amines
Earth (planet)
Nuclear magnetic resonance

Keywords

  • amide
  • amine
  • deoxygenative hydrogenation
  • manganese pincer complex
  • metal-ligand cooperation

ASJC Scopus subject areas

  • Catalysis

Cite this

Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal-Ligand Cooperation. / Zou, You Quan; Chakraborty, Subrata; Nerush, Alexander; Oren, Dror; Diskin-Posner, Yael; Ben-David, Yehoshoa; Milstein, David.

In: ACS Catalysis, Vol. 8, No. 9, 07.09.2018, p. 8014-8019.

Research output: Contribution to journalArticle

Zou, You Quan ; Chakraborty, Subrata ; Nerush, Alexander ; Oren, Dror ; Diskin-Posner, Yael ; Ben-David, Yehoshoa ; Milstein, David. / Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal-Ligand Cooperation. In: ACS Catalysis. 2018 ; Vol. 8, No. 9. pp. 8014-8019.
@article{af217905a1d6487e8a2c503c09c2b714,
title = "Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal-Ligand Cooperation",
abstract = "Deoxygenative hydrogenation of amides to amines homogeneously catalyzed by a complex of an Earth-abundant metal is presented. This manganese-catalyzed reaction features high efficiency and selectivity. A plausible reaction mechanism, involving metal-ligand cooperation of the manganese pincer complex, is proposed based on NMR studies and relevant stoichiometric reactions.",
keywords = "amide, amine, deoxygenative hydrogenation, manganese pincer complex, metal-ligand cooperation",
author = "Zou, {You Quan} and Subrata Chakraborty and Alexander Nerush and Dror Oren and Yael Diskin-Posner and Yehoshoa Ben-David and David Milstein",
year = "2018",
month = "9",
day = "7",
doi = "10.1021/acscatal.8b02902",
language = "English",
volume = "8",
pages = "8014--8019",
journal = "ACS Catalysis",
issn = "2155-5435",
publisher = "American Chemical Society",
number = "9",

}

TY - JOUR

T1 - Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal-Ligand Cooperation

AU - Zou, You Quan

AU - Chakraborty, Subrata

AU - Nerush, Alexander

AU - Oren, Dror

AU - Diskin-Posner, Yael

AU - Ben-David, Yehoshoa

AU - Milstein, David

PY - 2018/9/7

Y1 - 2018/9/7

N2 - Deoxygenative hydrogenation of amides to amines homogeneously catalyzed by a complex of an Earth-abundant metal is presented. This manganese-catalyzed reaction features high efficiency and selectivity. A plausible reaction mechanism, involving metal-ligand cooperation of the manganese pincer complex, is proposed based on NMR studies and relevant stoichiometric reactions.

AB - Deoxygenative hydrogenation of amides to amines homogeneously catalyzed by a complex of an Earth-abundant metal is presented. This manganese-catalyzed reaction features high efficiency and selectivity. A plausible reaction mechanism, involving metal-ligand cooperation of the manganese pincer complex, is proposed based on NMR studies and relevant stoichiometric reactions.

KW - amide

KW - amine

KW - deoxygenative hydrogenation

KW - manganese pincer complex

KW - metal-ligand cooperation

UR - http://www.scopus.com/inward/record.url?scp=85052283171&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85052283171&partnerID=8YFLogxK

U2 - 10.1021/acscatal.8b02902

DO - 10.1021/acscatal.8b02902

M3 - Article

AN - SCOPUS:85052283171

VL - 8

SP - 8014

EP - 8019

JO - ACS Catalysis

JF - ACS Catalysis

SN - 2155-5435

IS - 9

ER -