Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal-Ligand Cooperation

You Quan Zou, Subrata Chakraborty, Alexander Nerush, Dror Oren, Yael Diskin-Posner, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Deoxygenative hydrogenation of amides to amines homogeneously catalyzed by a complex of an Earth-abundant metal is presented. This manganese-catalyzed reaction features high efficiency and selectivity. A plausible reaction mechanism, involving metal-ligand cooperation of the manganese pincer complex, is proposed based on NMR studies and relevant stoichiometric reactions.

Original languageEnglish
Pages (from-to)8014-8019
Number of pages6
JournalACS Catalysis
Volume8
Issue number9
DOIs
Publication statusPublished - Sep 7 2018

Keywords

  • amide
  • amine
  • deoxygenative hydrogenation
  • manganese pincer complex
  • metal-ligand cooperation

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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