Abstract
The first example of a base-metal-catalyzed homogeneous hydrogenative coupling of nitriles and amines to selectively form secondary cross-imines is reported. The reaction is catalyzed under mild conditions by a well-defined (iPr-PNP)Fe(H)Br(CO) pincer pre-catalyst and catalytic tBuOK.
| Original language | English |
|---|---|
| Pages (from-to) | 2074-2078 |
| Number of pages | 5 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 56 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2017 |
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Keywords
- cross-coupling
- hydrogenation
- imines
- iron
- nitriles
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
Cite this
Chakraborty, S., Leitus, G., & Milstein, D. (2017). Iron-Catalyzed Mild and Selective Hydrogenative Cross-Coupling of Nitriles and Amines To Form Secondary Aldimines. Angewandte Chemie - International Edition, 56(8), 2074-2078. https://doi.org/10.1002/anie.201608537