Abstract
Great progress has been made in the past several decades concerning C-H bond functionalization. But despite many significant advances, a commercially viable large-scale process for selective alkane functionalization remains an unreached goal. Such conversions will require highly active, selective, and long-lived catalysts. In addition, essentially complete atom-economy will be required. Thus, any reagents used in transforming the alkanes must be almost free (e.g., O2, H2O, N2), or they should be incorporated into the desired large-scale product. Any side-products should be completely benign or have value as fuels (e.g., H2 or other alkanes). Progress and promising leads toward the development of such systems involving primarily molecular transition metal catalysts are described.
| Original language | English |
|---|---|
| Pages (from-to) | 620-626 |
| Number of pages | 7 |
| Journal | Accounts of Chemical Research |
| Volume | 50 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2017 |
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ASJC Scopus subject areas
- Chemistry(all)
Cite this
Large-scale selective functionalization of alkanes. / Goldberg, Karen I.; Goldman, Alan S.
In: Accounts of Chemical Research, Vol. 50, No. 3, 2017, p. 620-626.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Large-scale selective functionalization of alkanes
AU - Goldberg, Karen I.
AU - Goldman, Alan S
PY - 2017
Y1 - 2017
N2 - Great progress has been made in the past several decades concerning C-H bond functionalization. But despite many significant advances, a commercially viable large-scale process for selective alkane functionalization remains an unreached goal. Such conversions will require highly active, selective, and long-lived catalysts. In addition, essentially complete atom-economy will be required. Thus, any reagents used in transforming the alkanes must be almost free (e.g., O2, H2O, N2), or they should be incorporated into the desired large-scale product. Any side-products should be completely benign or have value as fuels (e.g., H2 or other alkanes). Progress and promising leads toward the development of such systems involving primarily molecular transition metal catalysts are described.
AB - Great progress has been made in the past several decades concerning C-H bond functionalization. But despite many significant advances, a commercially viable large-scale process for selective alkane functionalization remains an unreached goal. Such conversions will require highly active, selective, and long-lived catalysts. In addition, essentially complete atom-economy will be required. Thus, any reagents used in transforming the alkanes must be almost free (e.g., O2, H2O, N2), or they should be incorporated into the desired large-scale product. Any side-products should be completely benign or have value as fuels (e.g., H2 or other alkanes). Progress and promising leads toward the development of such systems involving primarily molecular transition metal catalysts are described.
UR - http://www.scopus.com/inward/record.url?scp=85018886180&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85018886180&partnerID=8YFLogxK
U2 - 10.1021/acs.accounts.6b00621
DO - 10.1021/acs.accounts.6b00621
M3 - Review article
C2 - 28945401
AN - SCOPUS:85018886180
VL - 50
SP - 620
EP - 626
JO - Accounts of Chemical Research
JF - Accounts of Chemical Research
SN - 0001-4842
IS - 3
ER -