Abstract
Photocleavage of a 2-nitrobenzyl group in a bioactive peptide amphiphile containing the Arg-Gly-Asp (RGD) epitope triggers a sol-to-gel transition as nanospheres are converted to nanofibers (see picture). This morphological change enhances the bioactivity of the nanostructures surrounding cells in three dimensions.
Original language | English |
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Pages (from-to) | 5946-5949 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 48 |
Issue number | 32 |
DOIs | |
Publication status | Published - Jul 27 2009 |
Keywords
- Amphiphiles
- Epitopes
- Gels
- Peptides
- Self-assembly
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)