Manganese-Catalyzed Direct Deoxygenation of Primary Alcohols

Jonathan O. Bauer, Subrata Chakraborty, David Milstein

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Deoxygenation of alcohols is an important tool in the repertoire of defunctionalization methods in modern synthetic chemistry. We report the base-metal-catalyzed direct deoxygenation of benzylic and aliphatic primary alcohols via oxidative dehydrogenation/Wolff-Kishner reduction. The reaction is catalyzed by a well-defined PNP pincer complex of Earth-abundant manganese, evolving H2, N2, and water as the only byproducts.

Original languageEnglish
Pages (from-to)4462-4466
Number of pages5
JournalACS Catalysis
Volume7
Issue number7
DOIs
Publication statusPublished - Jul 7 2017

Keywords

  • alcohols
  • deoxygenation
  • homogeneous catalysis
  • manganese complex
  • pincer complexes

ASJC Scopus subject areas

  • Catalysis

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