Manganese-Catalyzed Direct Deoxygenation of Primary Alcohols

Jonathan O. Bauer, Subrata Chakraborty, David Milstein

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Deoxygenation of alcohols is an important tool in the repertoire of defunctionalization methods in modern synthetic chemistry. We report the base-metal-catalyzed direct deoxygenation of benzylic and aliphatic primary alcohols via oxidative dehydrogenation/Wolff-Kishner reduction. The reaction is catalyzed by a well-defined PNP pincer complex of Earth-abundant manganese, evolving H2, N2, and water as the only byproducts.

Original languageEnglish
Pages (from-to)4462-4466
Number of pages5
JournalACS Catalysis
Volume7
Issue number7
DOIs
Publication statusPublished - Jul 7 2017

Fingerprint

Manganese
Alcohols
Dehydrogenation
Byproducts
Metals
Earth (planet)
Water

Keywords

  • alcohols
  • deoxygenation
  • homogeneous catalysis
  • manganese complex
  • pincer complexes

ASJC Scopus subject areas

  • Catalysis

Cite this

Manganese-Catalyzed Direct Deoxygenation of Primary Alcohols. / Bauer, Jonathan O.; Chakraborty, Subrata; Milstein, David.

In: ACS Catalysis, Vol. 7, No. 7, 07.07.2017, p. 4462-4466.

Research output: Contribution to journalArticle

Bauer, Jonathan O. ; Chakraborty, Subrata ; Milstein, David. / Manganese-Catalyzed Direct Deoxygenation of Primary Alcohols. In: ACS Catalysis. 2017 ; Vol. 7, No. 7. pp. 4462-4466.
@article{e5d52c5d22ee4ea18a4f72ec7b6043cc,
title = "Manganese-Catalyzed Direct Deoxygenation of Primary Alcohols",
abstract = "Deoxygenation of alcohols is an important tool in the repertoire of defunctionalization methods in modern synthetic chemistry. We report the base-metal-catalyzed direct deoxygenation of benzylic and aliphatic primary alcohols via oxidative dehydrogenation/Wolff-Kishner reduction. The reaction is catalyzed by a well-defined PNP pincer complex of Earth-abundant manganese, evolving H2, N2, and water as the only byproducts.",
keywords = "alcohols, deoxygenation, homogeneous catalysis, manganese complex, pincer complexes",
author = "Bauer, {Jonathan O.} and Subrata Chakraborty and David Milstein",
year = "2017",
month = "7",
day = "7",
doi = "10.1021/acscatal.7b01729",
language = "English",
volume = "7",
pages = "4462--4466",
journal = "ACS Catalysis",
issn = "2155-5435",
publisher = "American Chemical Society",
number = "7",

}

TY - JOUR

T1 - Manganese-Catalyzed Direct Deoxygenation of Primary Alcohols

AU - Bauer, Jonathan O.

AU - Chakraborty, Subrata

AU - Milstein, David

PY - 2017/7/7

Y1 - 2017/7/7

N2 - Deoxygenation of alcohols is an important tool in the repertoire of defunctionalization methods in modern synthetic chemistry. We report the base-metal-catalyzed direct deoxygenation of benzylic and aliphatic primary alcohols via oxidative dehydrogenation/Wolff-Kishner reduction. The reaction is catalyzed by a well-defined PNP pincer complex of Earth-abundant manganese, evolving H2, N2, and water as the only byproducts.

AB - Deoxygenation of alcohols is an important tool in the repertoire of defunctionalization methods in modern synthetic chemistry. We report the base-metal-catalyzed direct deoxygenation of benzylic and aliphatic primary alcohols via oxidative dehydrogenation/Wolff-Kishner reduction. The reaction is catalyzed by a well-defined PNP pincer complex of Earth-abundant manganese, evolving H2, N2, and water as the only byproducts.

KW - alcohols

KW - deoxygenation

KW - homogeneous catalysis

KW - manganese complex

KW - pincer complexes

UR - http://www.scopus.com/inward/record.url?scp=85024832944&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85024832944&partnerID=8YFLogxK

U2 - 10.1021/acscatal.7b01729

DO - 10.1021/acscatal.7b01729

M3 - Article

VL - 7

SP - 4462

EP - 4466

JO - ACS Catalysis

JF - ACS Catalysis

SN - 2155-5435

IS - 7

ER -