Abstract
Deoxygenation of alcohols is an important tool in the repertoire of defunctionalization methods in modern synthetic chemistry. We report the base-metal-catalyzed direct deoxygenation of benzylic and aliphatic primary alcohols via oxidative dehydrogenation/Wolff-Kishner reduction. The reaction is catalyzed by a well-defined PNP pincer complex of Earth-abundant manganese, evolving H2, N2, and water as the only byproducts.
| Original language | English |
|---|---|
| Pages (from-to) | 4462-4466 |
| Number of pages | 5 |
| Journal | ACS Catalysis |
| Volume | 7 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 7 2017 |
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Keywords
- alcohols
- deoxygenation
- homogeneous catalysis
- manganese complex
- pincer complexes
ASJC Scopus subject areas
- Catalysis
Cite this
Manganese-Catalyzed Direct Deoxygenation of Primary Alcohols. / Bauer, Jonathan O.; Chakraborty, Subrata; Milstein, David.
In: ACS Catalysis, Vol. 7, No. 7, 07.07.2017, p. 4462-4466.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Manganese-Catalyzed Direct Deoxygenation of Primary Alcohols
AU - Bauer, Jonathan O.
AU - Chakraborty, Subrata
AU - Milstein, David
PY - 2017/7/7
Y1 - 2017/7/7
N2 - Deoxygenation of alcohols is an important tool in the repertoire of defunctionalization methods in modern synthetic chemistry. We report the base-metal-catalyzed direct deoxygenation of benzylic and aliphatic primary alcohols via oxidative dehydrogenation/Wolff-Kishner reduction. The reaction is catalyzed by a well-defined PNP pincer complex of Earth-abundant manganese, evolving H2, N2, and water as the only byproducts.
AB - Deoxygenation of alcohols is an important tool in the repertoire of defunctionalization methods in modern synthetic chemistry. We report the base-metal-catalyzed direct deoxygenation of benzylic and aliphatic primary alcohols via oxidative dehydrogenation/Wolff-Kishner reduction. The reaction is catalyzed by a well-defined PNP pincer complex of Earth-abundant manganese, evolving H2, N2, and water as the only byproducts.
KW - alcohols
KW - deoxygenation
KW - homogeneous catalysis
KW - manganese complex
KW - pincer complexes
UR - http://www.scopus.com/inward/record.url?scp=85024832944&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85024832944&partnerID=8YFLogxK
U2 - 10.1021/acscatal.7b01729
DO - 10.1021/acscatal.7b01729
M3 - Article
AN - SCOPUS:85024832944
VL - 7
SP - 4462
EP - 4466
JO - ACS Catalysis
JF - ACS Catalysis
SN - 2155-5435
IS - 7
ER -