TY - JOUR
T1 - Manganese-Catalyzed Environmentally Benign Dehydrogenative Coupling of Alcohols and Amines to Form Aldimines and H2
T2 - A Catalytic and Mechanistic Study
AU - Mukherjee, Arup
AU - Nerush, Alexander
AU - Leitus, Gregory
AU - Shimon, Linda J W
AU - Ben David, Yehoshoa
AU - Espinosa Jalapa, Noel Angel
AU - Milstein, David
PY - 2016/4/20
Y1 - 2016/4/20
N2 - The catalytic dehydrogenative coupling of alcohols and amines to form aldimines represents an environmentally benign methodology in organic chemistry. This has been accomplished in recent years mainly with precious-metal-based catalysts. We present the dehydrogenative coupling of alcohols and amines to form imines and H2 that is catalyzed, for the first time, by a complex of the earth-abundant Mn. Detailed mechanistic study was carried out with the aid of NMR spectroscopy, intermediate isolation, and X-ray analysis.
AB - The catalytic dehydrogenative coupling of alcohols and amines to form aldimines represents an environmentally benign methodology in organic chemistry. This has been accomplished in recent years mainly with precious-metal-based catalysts. We present the dehydrogenative coupling of alcohols and amines to form imines and H2 that is catalyzed, for the first time, by a complex of the earth-abundant Mn. Detailed mechanistic study was carried out with the aid of NMR spectroscopy, intermediate isolation, and X-ray analysis.
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U2 - 10.1021/jacs.5b13519
DO - 10.1021/jacs.5b13519
M3 - Article
AN - SCOPUS:84964683497
VL - 138
SP - 4298
EP - 4301
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
SN - 0002-7863
IS - 13
ER -