Manganese Catalyzed Hydrogenation of Carbamates and Urea Derivatives

Uttam Kumar Das, Amit Kumar, Yehoshoa Ben-David, Mark A. Iron, David Milstein

Research output: Contribution to journalArticle

11 Citations (Scopus)


We report the hydrogenation of carbamates and urea derivatives, two of the most challenging carbonyl compounds to be hydrogenated, catalyzed for the first time by a complex of an earth-abundant metal. The hydrogenation reaction of these CO2-derived compounds, catalyzed by a manganese pincer complex, yields methanol in addition to amine and alcohol, which makes this methodology a sustainable alternative route for the conversion of CO2 to methanol, involving a base-metal catalyst. Moreover, the hydrogenation proceeds under mild pressure (20 bar). Our observations support a hydrogenation mechanism involving the Mn-H complex. A plausible catalytic cycle is proposed based on informative mechanistic experiments.

Original languageEnglish
Pages (from-to)12962-12966
Number of pages5
JournalJournal of the American Chemical Society
Issue number33
Publication statusPublished - Aug 21 2019

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Fingerprint Dive into the research topics of 'Manganese Catalyzed Hydrogenation of Carbamates and Urea Derivatives'. Together they form a unique fingerprint.

  • Cite this