Manganese-Catalyzed Hydrogenation of Esters to Alcohols

Noel Angel Espinosa-Jalapa, Alexander Nerush, Linda J W Shimon, Gregory Leitus, Liat Avram, Yehoshoa Ben-David, David Milstein

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105 Citations (Scopus)

Abstract

Homogeneous catalytic hydrogenation of esters to alcohols is an industrially important, environmentally benign reaction. While precious metal-based catalysts for this reaction are now well known, only very few catalysts based on first-row metal complexes were reported. Here we present the hydrogenation of esters catalyzed by a complex of earth-abundant manganese. The reaction proceeds under mild conditions and insight into the mechanism is provided based on an NMR study and the synthesis of novel Mn complexes postulated as intermediates.

Original languageEnglish
JournalChemistry - A European Journal
DOIs
Publication statusAccepted/In press - 2016

Keywords

  • Alcohols
  • Esters
  • Homogeneous catalysis
  • Manganese
  • Pincer complexes

ASJC Scopus subject areas

  • Chemistry(all)

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  • Cite this

    Espinosa-Jalapa, N. A., Nerush, A., Shimon, L. J. W., Leitus, G., Avram, L., Ben-David, Y., & Milstein, D. (Accepted/In press). Manganese-Catalyzed Hydrogenation of Esters to Alcohols. Chemistry - A European Journal. https://doi.org/10.1002/chem.201604991