Manganese-Catalyzed Hydrogenation of Esters to Alcohols

Noel Angel Espinosa-Jalapa, Alexander Nerush, Linda J W Shimon, Gregory Leitus, Liat Avram, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

Homogeneous catalytic hydrogenation of esters to alcohols is an industrially important, environmentally benign reaction. While precious metal-based catalysts for this reaction are now well known, only very few catalysts based on first-row metal complexes were reported. Here we present the hydrogenation of esters catalyzed by a complex of earth-abundant manganese. The reaction proceeds under mild conditions and insight into the mechanism is provided based on an NMR study and the synthesis of novel Mn complexes postulated as intermediates.

Original languageEnglish
JournalChemistry - A European Journal
DOIs
Publication statusAccepted/In press - 2016

Fingerprint

Manganese
Hydrogenation
Esters
Alcohols
Catalysts
Coordination Complexes
Precious metals
Metal complexes
Earth (planet)
Nuclear magnetic resonance

Keywords

  • Alcohols
  • Esters
  • Homogeneous catalysis
  • Manganese
  • Pincer complexes

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Espinosa-Jalapa, N. A., Nerush, A., Shimon, L. J. W., Leitus, G., Avram, L., Ben-David, Y., & Milstein, D. (Accepted/In press). Manganese-Catalyzed Hydrogenation of Esters to Alcohols. Chemistry - A European Journal. https://doi.org/10.1002/chem.201604991

Manganese-Catalyzed Hydrogenation of Esters to Alcohols. / Espinosa-Jalapa, Noel Angel; Nerush, Alexander; Shimon, Linda J W; Leitus, Gregory; Avram, Liat; Ben-David, Yehoshoa; Milstein, David.

In: Chemistry - A European Journal, 2016.

Research output: Contribution to journalArticle

Espinosa-Jalapa NA, Nerush A, Shimon LJW, Leitus G, Avram L, Ben-David Y et al. Manganese-Catalyzed Hydrogenation of Esters to Alcohols. Chemistry - A European Journal. 2016. https://doi.org/10.1002/chem.201604991
Espinosa-Jalapa, Noel Angel ; Nerush, Alexander ; Shimon, Linda J W ; Leitus, Gregory ; Avram, Liat ; Ben-David, Yehoshoa ; Milstein, David. / Manganese-Catalyzed Hydrogenation of Esters to Alcohols. In: Chemistry - A European Journal. 2016.
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