Melting mechanisms of DNA-linked nanocomposite systems

Sung Yong Park, George C Schatz

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The origins of sharp melting transitions in DNA-linked nanocomposite systems are discussed. Under typical experimental conditions, the local salt concentration in DNA-linked nanocomposite systems is important, leading to salt-induced condensation both in DNA-linked gold nanoparticle systems and polymer-DNA hybrid systems that leads to cooperative melting. Although this coop-erativity is supported by the experimental results, which have measured the number of cooperative DNA sequences, and molecular dynamics simulations, some recent experiments suggest that the sharp melting does not arise entirely from salt condensation. We point out that this discrepancy can be resolved by considering the contribution of large clusters, which only exist below the melting transition.

Original languageEnglish
Title of host publication2nd Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2005
Pages206-213
Number of pages8
Publication statusPublished - 2005
Event2nd Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2005 - Snowbird, UT, United States
Duration: Apr 24 2005Apr 28 2005

Other

Other2nd Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2005
CountryUnited States
CitySnowbird, UT
Period4/24/054/28/05

Fingerprint

Nanocomposites
Melting
DNA
Salts
Condensation
DNA sequences
Hybrid systems
Molecular dynamics
Gold
Nanoparticles
Computer simulation
Polymers
Experiments

ASJC Scopus subject areas

  • Hardware and Architecture
  • Electrical and Electronic Engineering

Cite this

Park, S. Y., & Schatz, G. C. (2005). Melting mechanisms of DNA-linked nanocomposite systems. In 2nd Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2005 (pp. 206-213)

Melting mechanisms of DNA-linked nanocomposite systems. / Park, Sung Yong; Schatz, George C.

2nd Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2005. 2005. p. 206-213.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Park, SY & Schatz, GC 2005, Melting mechanisms of DNA-linked nanocomposite systems. in 2nd Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2005. pp. 206-213, 2nd Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2005, Snowbird, UT, United States, 4/24/05.
Park SY, Schatz GC. Melting mechanisms of DNA-linked nanocomposite systems. In 2nd Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2005. 2005. p. 206-213
Park, Sung Yong ; Schatz, George C. / Melting mechanisms of DNA-linked nanocomposite systems. 2nd Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2005. 2005. pp. 206-213
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