METAL CENTERS OF CYTOCHROME c OXIDASE: STRUCTURES AND INTERACTIONS.

David F. Blair; Craig T. Martin; Jeff Gelles; Hsin Wang; Gary W Brudvig; Tom H. Stevens; Sunney I. Chan

METAL CENTERS OF CYTOCHROME c OXIDASE: STRUCTURES AND INTERACTIONS.

David F. Blair, Craig T. Martin, Jeff Gelles, Hsin Wang, Gary W Brudvig, Tom H. Stevens, Sunney I. Chan

Yale University

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Abstract

Studies directed toward the elucidation of the structures of the metal centers in cytochrome c oxidase are reviewed. Progress towards an understanding of the interactions between these centers and their spatial distributions within the protein is also presented. The authors have employed nitric oxide (NO), as well as other exogenous ligands, to probe the O//2 reduction site of the enzyme. In addition, we have isolated auxotrophs of Saccharomyces cerevisiae in order to metabolically incorporate isotopically substituted amino acids into the yeast protein.

Original language	English
Pages (from-to)	43-53
Number of pages	11
Journal	Chemica scripta
Volume	21
Issue number	1-5
Publication status	Published - 1982

ASJC Scopus subject areas

Engineering(all)

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abstract = "Studies directed toward the elucidation of the structures of the metal centers in cytochrome c oxidase are reviewed. Progress towards an understanding of the interactions between these centers and their spatial distributions within the protein is also presented. The authors have employed nitric oxide (NO), as well as other exogenous ligands, to probe the O//2 reduction site of the enzyme. In addition, we have isolated auxotrophs of Saccharomyces cerevisiae in order to metabolically incorporate isotopically substituted amino acids into the yeast protein.",

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AU - Blair, David F.

AU - Martin, Craig T.

AU - Gelles, Jeff

AU - Wang, Hsin

AU - Brudvig, Gary W

AU - Stevens, Tom H.

AU - Chan, Sunney I.

PY - 1982

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