METAL CENTERS OF CYTOCHROME c OXIDASE

STRUCTURES AND INTERACTIONS.

David F. Blair, Craig T. Martin, Jeff Gelles, Hsin Wang, Gary W Brudvig, Tom H. Stevens, Sunney I. Chan

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Studies directed toward the elucidation of the structures of the metal centers in cytochrome c oxidase are reviewed. Progress towards an understanding of the interactions between these centers and their spatial distributions within the protein is also presented. The authors have employed nitric oxide (NO), as well as other exogenous ligands, to probe the O//2 reduction site of the enzyme. In addition, we have isolated auxotrophs of Saccharomyces cerevisiae in order to metabolically incorporate isotopically substituted amino acids into the yeast protein.

Original languageEnglish
Pages (from-to)43-53
Number of pages11
JournalChemica scripta
Volume21
Issue number1-5
Publication statusPublished - 1982

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Nitric oxide
Yeast
Spatial distribution
Amino acids
Enzymes
Ligands
Proteins
Metals
Fungal Proteins
Electron Transport Complex IV
Oxidoreductases

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Blair, D. F., Martin, C. T., Gelles, J., Wang, H., Brudvig, G. W., Stevens, T. H., & Chan, S. I. (1982). METAL CENTERS OF CYTOCHROME c OXIDASE: STRUCTURES AND INTERACTIONS. Chemica scripta, 21(1-5), 43-53.

METAL CENTERS OF CYTOCHROME c OXIDASE : STRUCTURES AND INTERACTIONS. / Blair, David F.; Martin, Craig T.; Gelles, Jeff; Wang, Hsin; Brudvig, Gary W; Stevens, Tom H.; Chan, Sunney I.

In: Chemica scripta, Vol. 21, No. 1-5, 1982, p. 43-53.

Research output: Contribution to journalArticle

Blair, DF, Martin, CT, Gelles, J, Wang, H, Brudvig, GW, Stevens, TH & Chan, SI 1982, 'METAL CENTERS OF CYTOCHROME c OXIDASE: STRUCTURES AND INTERACTIONS.', Chemica scripta, vol. 21, no. 1-5, pp. 43-53.
Blair DF, Martin CT, Gelles J, Wang H, Brudvig GW, Stevens TH et al. METAL CENTERS OF CYTOCHROME c OXIDASE: STRUCTURES AND INTERACTIONS. Chemica scripta. 1982;21(1-5):43-53.
Blair, David F. ; Martin, Craig T. ; Gelles, Jeff ; Wang, Hsin ; Brudvig, Gary W ; Stevens, Tom H. ; Chan, Sunney I. / METAL CENTERS OF CYTOCHROME c OXIDASE : STRUCTURES AND INTERACTIONS. In: Chemica scripta. 1982 ; Vol. 21, No. 1-5. pp. 43-53.
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