Molecular recognition in homogeneous transition metal catalysis: A biomimetic strategy for high selectivity

Siddartha Das; Gary W Brudvig; Robert H. Crabtree

doi:10.1039/b710355g

Molecular recognition in homogeneous transition metal catalysis: A biomimetic strategy for high selectivity

Siddartha Das, Gary W Brudvig, Robert H. Crabtree

Yale University

Research output: Contribution to journal › Article

11 Citations (Scopus)

Abstract

Traditional methods for selectivity control in homogeneous transition metal catalysis either employ steric effects in a binding pocket or chelate control. In a supramolecular strategy, encapsulation of the substrate can provide useful shape and size selectivity. A fully developed molecular recognition strategy involving hydrogen bonding or solvophobic forces has given almost completely regioselective functionalization of remote, unactivated C-H bonds.

Original language	English
Pages (from-to)	413-424
Number of pages	12
Journal	Chemical Communications
Volume	8
Issue number	4
DOIs	https://doi.org/10.1039/b710355g
Publication status	Published - 2008

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ASJC Scopus subject areas

Chemistry(all)

Cite this

Das, S., Brudvig, G. W., & Crabtree, R. H. (2008). Molecular recognition in homogeneous transition metal catalysis: A biomimetic strategy for high selectivity. Chemical Communications, 8(4), 413-424. https://doi.org/10.1039/b710355g

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Access to Document

10.1039/b710355g