Molecular recognition in homogeneous transition metal catalysis

A biomimetic strategy for high selectivity

Siddartha Das, Gary W Brudvig, Robert H. Crabtree

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Traditional methods for selectivity control in homogeneous transition metal catalysis either employ steric effects in a binding pocket or chelate control. In a supramolecular strategy, encapsulation of the substrate can provide useful shape and size selectivity. A fully developed molecular recognition strategy involving hydrogen bonding or solvophobic forces has given almost completely regioselective functionalization of remote, unactivated C-H bonds.

Original languageEnglish
Pages (from-to)413-424
Number of pages12
JournalChemical Communications
Volume8
Issue number4
DOIs
Publication statusPublished - 2008

Fingerprint

Molecular recognition
Catalyst selectivity
Biomimetics
Catalysis
Transition metals
Encapsulation
Hydrogen bonds
Substrates

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Molecular recognition in homogeneous transition metal catalysis : A biomimetic strategy for high selectivity. / Das, Siddartha; Brudvig, Gary W; Crabtree, Robert H.

In: Chemical Communications, Vol. 8, No. 4, 2008, p. 413-424.

Research output: Contribution to journalArticle

@article{739c7294dc2d4cb4b15e2853888bafc2,
title = "Molecular recognition in homogeneous transition metal catalysis: A biomimetic strategy for high selectivity",
abstract = "Traditional methods for selectivity control in homogeneous transition metal catalysis either employ steric effects in a binding pocket or chelate control. In a supramolecular strategy, encapsulation of the substrate can provide useful shape and size selectivity. A fully developed molecular recognition strategy involving hydrogen bonding or solvophobic forces has given almost completely regioselective functionalization of remote, unactivated C-H bonds.",
author = "Siddartha Das and Brudvig, {Gary W} and Crabtree, {Robert H.}",
year = "2008",
doi = "10.1039/b710355g",
language = "English",
volume = "8",
pages = "413--424",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "4",

}

TY - JOUR

T1 - Molecular recognition in homogeneous transition metal catalysis

T2 - A biomimetic strategy for high selectivity

AU - Das, Siddartha

AU - Brudvig, Gary W

AU - Crabtree, Robert H.

PY - 2008

Y1 - 2008

N2 - Traditional methods for selectivity control in homogeneous transition metal catalysis either employ steric effects in a binding pocket or chelate control. In a supramolecular strategy, encapsulation of the substrate can provide useful shape and size selectivity. A fully developed molecular recognition strategy involving hydrogen bonding or solvophobic forces has given almost completely regioselective functionalization of remote, unactivated C-H bonds.

AB - Traditional methods for selectivity control in homogeneous transition metal catalysis either employ steric effects in a binding pocket or chelate control. In a supramolecular strategy, encapsulation of the substrate can provide useful shape and size selectivity. A fully developed molecular recognition strategy involving hydrogen bonding or solvophobic forces has given almost completely regioselective functionalization of remote, unactivated C-H bonds.

UR - http://www.scopus.com/inward/record.url?scp=38049155811&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38049155811&partnerID=8YFLogxK

U2 - 10.1039/b710355g

DO - 10.1039/b710355g

M3 - Article

VL - 8

SP - 413

EP - 424

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 4

ER -