N-Substituted Hydrazones by Manganese-Catalyzed Coupling of Alcohols with Hydrazine: Borrowing Hydrogen and Acceptorless Dehydrogenation in One System

Uttam Kumar Das, Yehoshoa Ben-David, Yael Diskin-Posner, David Milstein

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

An unprecedented one-step synthesis of N-substituted hydrazones by coupling of alcohols with hydrazine is reported. This partial hydrogen-borrowing reaction is catalyzed by a new manganese pincer complex under mild reaction conditions, thus liberating water and dihydrogen as the only byproducts. Mechanistic insight, based on the observation of intermediates, is provided.

Original languageEnglish
Pages (from-to)2179-2182
Number of pages4
JournalAngewandte Chemie - International Edition
Volume57
Issue number8
DOIs
Publication statusPublished - Feb 19 2018

Keywords

  • dehydrogenation
  • hydrazones
  • hydrogen borrowing
  • manganese
  • reaction mechanisms

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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